SCHEMBL8094638

SCHEMBL8094638

ClSc1nnnn1-c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 15/20 0.62
LMNA P02545 6/20 0.60
TSHR P16473 4/20 0.60
SMN1; SMN2 Q16637 4/20 0.60
HPGD P15428 2/20 0.60
MAPT P10636 5/20 0.57
POLB P06746 2/20 0.57
KMT2A Q03164 2/20 0.57
MEN1 O00255 1/20 0.57
HTT P42858 4/20 0.55
NPSR1 Q6W5P4 1/20 0.54
CCR6 P51684 1/20 0.53
CACNA1B Q00975 1/20 0.53
APBA1 Q02410 1/20 0.53
GAA P10253 2/20 0.53
NPC1 O15118 1/20 0.53
NFKB1 P19838 1/20 0.53
RAB9A P51151 1/20 0.53
NFKB2 Q00653 1/20 0.53
RELA Q04206 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2395370 0.84 ALDH1A1 (0.66) ALDH1A1LMNATSHRSMN1; SMN2HPGD
SCHEMBL11202055 0.84 ALDH1A1 (0.73) ALDH1A1LMNATSHRSMN1; SMN2HPGD
SCHEMBL10912553 0.81 ALDH1A1 (0.63) ALDH1A1LMNATSHRSMN1; SMN2HPGD
SCHEMBL6930554 0.81 ALDH1A1 (0.62) ALDH1A1LMNATSHRSMN1; SMN2HPGD
SCHEMBL3485204 0.81 ALDH1A1 (0.62) ALDH1A1LMNATSHRSMN1; SMN2HPGD
SCHEMBL6930563 0.81 ALDH1A1 (0.67) ALDH1A1LMNATSHRSMN1; SMN2HPGD
SCHEMBL3485202 0.81 ALDH1A1 (0.62) ALDH1A1LMNATSHRSMN1; SMN2HPGD
SCHEMBL9137875 0.80 ALDH1A1 (0.71) ALDH1A1LMNATSHRSMN1; SMN2HPGD
SCHEMBL17097394 0.79 ALDH1A1 (0.62) ALDH1A1LMNATSHRSMN1; SMN2HPGD
SCHEMBL10721861 0.79 ALDH1A1 (0.55) ALDH1A1LMNATSHRSMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0763526-B1 Process for preparation of 4-mercapto-1-naphthol compounds TULALIP CONSULTORIA COMERCIAL (PT) 2000-12-06 EP disclosed
US-5693846-A Process for preparation of 4-mercapto-1-naphthol compounds IMATION CORP. (US) 1997-12-02 US disclosed
EP-0763526-A1 Process for preparation of 4-mercapto-1-naphthol compounds MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-03-19 EP disclosed
EP-0285176-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1994-06-08 EP disclosed
US-5202225-A High speed, high efficiency FUJI PHOTO FILM CO., LTD. (JP) 1993-04-13 US disclosed
US-5118597-A Sharpness, grainness, color reproduction FUJI PHOTO FILM CO., LTD. (JP) 1992-06-02 US disclosed
US-4985336-A Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-01-15 US disclosed
US-4933989-A Excellent color reproduction; sharpness FUJI PHOTO FILM CO. 1990-06-12 US disclosed
US-4873179-A MOLD RESISTANCE; ANTISOILANTS; COLORFASTNESS; RELEASE OF DEVELOPMENT INHIBITOR FUJI PHOTO FILM CO., LTD. (JP) 1989-10-10 US disclosed
EP-0285176-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1988-10-05 EP disclosed
US-4088491-A COLOR PHOTOGRAPHY, THIOETHERS, NONDIFFUSING AGFA-GEVAERT AKTIENGESELLSCHAFT (DT) 1978-05-09 US disclosed
US-4063950-A DEVELOPMENT INHIBITOR RELEASING COMPOUND, SILVER HALIDE EMULSIONS ON KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1977-12-20 US disclosed
US-4052213-A OXAZOLINONE-2-COMPOUNDS CONTAINING A MERCAPTO GROUP AGFA-GEVAERT, A.G. (DT) 1977-10-04 US disclosed
US-4046574-A COLOR PHOTOGRAPHIC MATERIAL WITH HOMOPHTHALIMIDE THIOETHER DEVELOPMENT INHIBITOR AGFA-GEVAERT, AKTIENGESELLSCHAFT (DT) 1977-09-06 US disclosed
US-3961959-A DEVELOPMENT RELEASING INHIBITOR KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1976-06-08 US disclosed
US-3958993-A SULFUR CONTAINING ORGANIC COMPOUND KONISHIROKU PHOTO INDUSTRY CO., LTD. (JA) 1976-05-25 US disclosed