SCHEMBL6930563

SCHEMBL6930563

CSc1nnnn1-c1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 14/20 0.67
SMN1; SMN2 Q16637 3/20 0.66
LMNA P02545 5/20 0.60
TSHR P16473 3/20 0.60
HPGD P15428 2/20 0.60
HTT P42858 3/20 0.59
POLB P06746 3/20 0.57
MAPT P10636 3/20 0.57
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
GAA P10253 2/20 0.54
TP53 P04637 1/20 0.54
MAPK1 P28482 1/20 0.54
HKDC1 Q2TB90 1/20 0.54
TDP1 Q9NUW8 2/20 0.53
NPC1 O15118 1/20 0.53
NFKB1 P19838 1/20 0.53
RAB9A P51151 1/20 0.53
NFKB2 Q00653 1/20 0.53
RELA Q04206 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13539392 0.85 ALDH1A1 (0.63) ALDH1A1SMN1; SMN2LMNATSHRHPGD
SCHEMBL11202055 0.84 ALDH1A1 (0.73) ALDH1A1SMN1; SMN2LMNATSHRHPGD
SCHEMBL2395370 0.84 ALDH1A1 (0.66) ALDH1A1SMN1; SMN2LMNATSHRHPGD
SCHEMBL7396129 0.81 ALDH1A1 (0.57) ALDH1A1SMN1; SMN2LMNATSHRHPGD
SCHEMBL8438530 0.81 SMN1; SMN2 (0.67) ALDH1A1SMN1; SMN2LMNATSHRHPGD
SCHEMBL10912553 0.81 ALDH1A1 (0.63) ALDH1A1SMN1; SMN2LMNATSHRHPGD
SCHEMBL10664251 0.81 SMN1; SMN2 (0.70) ALDH1A1SMN1; SMN2LMNATSHRHPGD
SCHEMBL15337450 0.81 SMN1; SMN2 (0.70) ALDH1A1SMN1; SMN2LMNATSHRHPGD
SCHEMBL3485202 0.81 ALDH1A1 (0.62) ALDH1A1SMN1; SMN2LMNATSHRHPGD
SCHEMBL8094638 0.81 ALDH1A1 (0.62) ALDH1A1SMN1; SMN2LMNATSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004101572-A1 7-GLUTARYL IMIDE CEPHALOSPORANIC ACID DERIVATIVES AND PROCESS FOR PREPARING IT CKD BIO CORPORATION (KR) 2004-11-25 WO claimed
US-4504478-A Cephalosporin-1-oxide derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (FR) 1985-03-12 US claimed
US-4497949-A PHOTOTHERMOGRAPHY;COLOR FILMS;STORAGE STABILITY;ANTIFOGGING AGENTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-02-05 US claimed
US-4492692-A BACTERICIDE IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-01-08 US claimed
US-4463173-A ANTIBIOTIC, BACTERICIDE ICI PHARMA (FR) 1984-07-31 US claimed
EP-0031708-B1 CEPHALOSPORIN DERIVATIVES, PROCESSES FOR THEIR MANUFACTURE, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND INTERMEDIATES THEREFOR ICI PHARMA (FR) 1984-06-13 EP claimed
EP-0082648-A2 Cephalosporin derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-06-29 EP claimed
EP-0075434-A2 Cephalosporins, their preparation and their pharmaceutical compositions ICI PHARMA (FR) 1983-03-30 EP claimed
EP-0072608-A2 Process for the preparation of cephalosporin derivatives IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-02-23 EP claimed
EP-0031708-A2 Cephalosporin derivatives, processes for their manufacture, pharmaceutical compositions containing them and intermediates therefor ICI PHARMA (FR) 1981-07-08 EP claimed
US-4105656-A PROCESS FOR PREPARING 3-N-MONOSUBSTITUTED AMINO-4-SUBSTITUTED-5-PYRAZOLONES FUJI PHOTO FILM CO., LTD. (JP) 1978-08-08 US claimed
US-4003910-A SELENIUM OR SULFUR CONTAINING PHOTOGRAPHIC ADDITIVES; TRIETHYL-OXONIUM FLUOROBORATE POLAROID CORPORATION (US) 1977-01-18 US claimed
US-20240336711-A1 REAGENTS AND METHODS FOR ALIPHATIC CARBON-HYDROGEN BOND FUNCTIONALIZATION THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2024-10-10 US disclosed
US-20230161255-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-25 US disclosed
US-20230161255-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-25 US disclosed
US-20230161252-A1 POSITIVE RESIST COMPOSITION AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-05-25 US disclosed
EP-0031708-A2 Cephalosporin derivatives, processes for their manufacture, pharmaceutical compositions containing them and intermediates therefor ICI PHARMA (FR) 1981-07-08 EP disclosed
US-4142894-A COLOR PHOTOGRAPHY; METHACRYLIC ACID-METHYL METHACRYLATE MATTING AGENT FUJI PHOTO FILM CO., LTD. (JP) 1979-03-06 US disclosed
US-4105656-A PROCESS FOR PREPARING 3-N-MONOSUBSTITUTED AMINO-4-SUBSTITUTED-5-PYRAZOLONES FUJI PHOTO FILM CO., LTD. (JP) 1978-08-08 US disclosed
US-4003910-A SELENIUM OR SULFUR CONTAINING PHOTOGRAPHIC ADDITIVES; TRIETHYL-OXONIUM FLUOROBORATE POLAROID CORPORATION (US) 1977-01-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240336711-A1 REAGENTS AND METHODS FOR ALIPHATIC CARBON-HYDROGEN BOND FUNCTIONALIZATION NCF1, SHROOM3, NPM1 ALDH1A1 2010/4885SMN1; SMN2 2305/4885LMNA 2104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.