Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 2/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 4/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MDM4 | O15151 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | MMP16 | P51512 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FABP7 | O15540 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28069714 | 0.82 | FABP5 (0.45) | FABP5MDM2KIF11MDM4TP53 | |
| SCHEMBL3485726 | 0.80 | FABP5 (0.41) | FABP5GAAKMT2AFABP7 | |
| SCHEMBL6298097 | 0.79 | FABP5 (0.41) | FABP5PTGS1AKR1C3AKR1C2GAA | |
| SCHEMBL8752790 | 0.79 | NPC1 (0.41) | FABP5KMT2A | |
| SCHEMBL28191790 | 0.77 | NPC1 (0.39) | FABP5GAAKMT2A | |
| SCHEMBL9730060 | 0.76 | MDM2 (0.47) | FABP5MDM2MDM4TP53KMT2A | |
| SCHEMBL29965197 | 0.75 | FABP5 (0.47) | FABP5MDM2KIF11GAAMDM4 | |
| SCHEMBL31194380 | 0.73 | MDM2 (0.40) | FABP5MDM2MDM4TP53KMT2A | |
| SCHEMBL29521535 | 0.73 | MEN1 (0.49) | TP53KMT2A | |
| SCHEMBL27082137 | 0.73 | NPC1 (0.40) | FABP5MDM2GAATP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316595-B1 | PNA synthesis using a base-labile amino protecting group | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2001-11-13 | — | — | US | disclosed |
| US-6121418-A | PNA synthesis using a base-labile amino protecting group | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-09-19 | — | — | US | disclosed |