SCHEMBL34865

SCHEMBL34865

Cc1cccc(-c2nc3ccc(-c4ccc5[nH]c(C)nc5c4)cc3[nH]2)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.69
RAB9A P51151 4/20 0.69
MEN1 O00255 3/20 0.69
POLB P06746 3/20 0.69
KMT2A Q03164 3/20 0.69
SMN1; SMN2 Q16637 2/20 0.69
KDM4E B2RXH2 2/20 0.60
ALDH1A1 P00352 2/20 0.60
MAPT P10636 2/20 0.60
GFER P55789 2/20 0.60
GAA P10253 2/20 0.60
GLA P06280 1/20 0.60
RXFP1 Q9HBX9 1/20 0.60
NPBWR1 P48145 1/20 0.59
TP53 P04637 1/20 0.55
PKM P14618 1/20 0.55
HPGD P15428 1/20 0.55
MMP2 P08253 2/20 0.53
MMP9 P14780 2/20 0.53
MMP8 P22894 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12999376 1.00 NPC1 (0.69) NPC1RAB9AMEN1POLBKMT2A
SCHEMBL11911271 0.95 NPC1 (0.59) NPC1RAB9AMEN1POLBKMT2A
SCHEMBL35046 0.95 NPC1 (0.72) NPC1RAB9AMEN1POLBKMT2A
SCHEMBL34879 0.93 RAB9A (0.74) NPC1RAB9AMEN1POLBKMT2A
SCHEMBL26357001 0.91 NPC1 (0.67) NPC1RAB9AMEN1POLBKMT2A
SCHEMBL11931988 0.88 NPC1 (0.74) NPC1RAB9AMEN1POLBKMT2A
SCHEMBL14193946 0.88 NPC1 (0.74) NPC1RAB9AMEN1POLBKMT2A
SCHEMBL34854 0.88 NPBWR1 (0.61) NPC1RAB9AMEN1POLBKMT2A
SCHEMBL13680581 0.88 RAB9A (0.59) NPC1RAB9AMEN1POLBKMT2A
SCHEMBL34856 0.87 MEN1 (0.68) NPC1RAB9AMEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11799112-B2 Polybenzimidazole (PBI) membranes for redox flow batteries UNIVERSITY OF SOUTH CAROLINA (US) 2023-10-24 US disclosed
US-11777124-B2 Proton-conducting PBI membrane processing with enhanced performance and durability UNIVERSITY OF SOUTH CAROLINA (US) 2023-10-03 US disclosed
WO-2023160073-A1 HOLLOW FIBER SEPERATION MEMBRANE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF 中国石油化工股份有限公司 2023-08-31 WO disclosed
US-10640645-B2 Polyisoindolinone compositions, methods of manufacture, and compositions and articles formed therefrom SABIC GLOBAL TECHNOLOGIES (NL) 2020-05-05 US disclosed
US-20190127575-A1 POLYISOINDOLINONE COMPOSITIONS, METHODS OF MANUFACTURE, AND COMPOSITIONS AND ARTICLES FORMED THEREFROM SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2019-05-02 US disclosed
US-9997791-B2 Membrane electrode units for high temperature fuel cells with improved stability BASF SE (DE) 2018-06-12 US disclosed
US-20180123155-A1 PROTON-CONDUCTING MEMBRANE, METHOD FOR THEIR PRODUCTION AND THEIR USE IN ELECTROCHEMICAL CELLS BASF SE (DE) 2018-05-03 US disclosed
US-9825320-B2 Process for the manufacture of membrane electrode units BASF SE (DE) 2017-11-21 US disclosed
US-9812725-B2 Proton-conducting membrane and use thereof BASF SE (DE) 2017-11-07 US disclosed
US-9812725-B2 Proton-conducting membrane and use thereof BASF SE (DE) 2017-11-07 US disclosed
US-20070248889-A1 Membrane Electrode Units and Fuel Cells with an Increased Service Life PEMEAS GMBH (DE) 2007-10-25 US disclosed
US-20070248863-A1 Membrane-Electrode Unit and Fuel Elements with Increased Service Life BASF FUEL CELL GMBH (DE) 2007-10-25 US disclosed
US-20070218335-A1 POLYMER HAVING OXOCARBON GROUP, AND USE THEREOF KAO CORPORATION (JP) 2007-09-20 US disclosed
US-20070202415-A1 Proton-Conducting Polymer Membrane Comprising At Least One Porous Carrier Material, And Use Thereof In Fuel Cells PEMEAS GMBH (DE) 2007-08-30 US disclosed
US-20070203252-A1 Anisotropic Shaped Bodies, Method For The Production And Utilization Of Anisotropic Shaped Bodies PEMEAS GMBH (DE) 2007-08-30 US disclosed
US-7244811-B2 Method for the treatment of polyazole films PEMEAS GMBH (DE) 2007-07-17 US disclosed
US-20070151926-A1 HIGH-MOLECULAR-WEIGHT POLYAZOLES USED AS PROTON CONDUCTING MEMBRANES BASF FUEL CELL GMBH (DE) 2007-07-05 US disclosed
US-7235320-B2 Proton-conducting membrane and use thereof PEMEAS GMBH (DE) 2007-06-26 US disclosed
US-20070102361-A1 Polyazole-based polymer films BASF FUEL CELL GMBH (DE) 2007-05-10 US disclosed
US-20070055045-A1 Proton-conducting polymer membrane containing polymers with sulfonic acid groups that are covalently bonded to aromatic groups, membrane electrode unit, and use thereof in fuel cells PEMEAS GMBH (DE) 2007-03-08 US disclosed