SCHEMBL35046

SCHEMBL35046

Cc1cccc(-c2nc3ccc(-c4ccc5nc(C)[nH]c5c4)cc3[nH]2)c1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.72
RAB9A P51151 5/20 0.72
MEN1 O00255 3/20 0.72
POLB P06746 3/20 0.72
KMT2A Q03164 3/20 0.72
SMN1; SMN2 Q16637 2/20 0.72
KDM4E B2RXH2 2/20 0.66
ALDH1A1 P00352 2/20 0.66
MAPT P10636 2/20 0.66
GFER P55789 2/20 0.66
GAA P10253 2/20 0.66
GLA P06280 1/20 0.66
RXFP1 Q9HBX9 1/20 0.66
NPBWR1 P48145 1/20 0.64
TP53 P04637 1/20 0.60
PKM P14618 1/20 0.60
HPGD P15428 1/20 0.60
MMP2 P08253 2/20 0.57
MMP9 P14780 2/20 0.57
MMP8 P22894 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12999376 0.95 NPC1 (0.69) NPC1RAB9AMEN1POLBKMT2A
SCHEMBL34865 0.95 NPC1 (0.69) NPC1RAB9AMEN1POLBKMT2A
SCHEMBL13680581 0.93 RAB9A (0.59) NPC1RAB9AMEN1POLBKMT2A
SCHEMBL21905249 0.91 DHODH (0.58) NPC1RAB9AMEN1POLBKMT2A
SCHEMBL34854 0.90 NPBWR1 (0.61) NPC1RAB9AMEN1POLBKMT2A
SCHEMBL11911271 0.89 NPC1 (0.59) NPC1RAB9AMEN1POLBKMT2A
SCHEMBL14665617 0.88 NPC1 (0.81) NPC1RAB9AMEN1POLBKMT2A
SCHEMBL14665476 0.88 NPC1 (0.75) NPC1RAB9AMEN1POLBKMT2A
SCHEMBL34879 0.87 RAB9A (0.74) NPC1RAB9AMEN1POLBKMT2A
SCHEMBL14346007 0.87 NPC1 (0.78) NPC1RAB9AMEN1POLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230302441-A1 WELL DEFINED QUATERNARY AMMONIUM FUNCTIONALIZED QUATERPHENYLENE POLYMER DERIVATIVES FOR LOW AND HIGH TEMPERATURE POLYMER ELECTROLYTE MEMBRANE FUEL CELLS ADVENT TECHNOLOGIES HOLDINGS, INC. 2023-09-28 US disclosed
US-20170266652-A1 FUNCTIONALIZED MAIN CHAIN POLYMERS HÄRING THOMAS (DE) 2017-09-21 US disclosed
US-9680156-B2 Composition, polymer thereof, electrode and electrolyte membrane for fuel cell, and fuel cell including the same SAMSUNG ELECTRONICS CO., LTD (KR) 2017-06-13 US disclosed
US-20170125832-A1 POLYMER ELECTROLYTE COMPOSITION AND POLYMER ELECTROLYTE MEMBRANE, POLYMER ELECTROLYTE MEMBRANE WITH CATALYST LAYER, MEMBRANE ELECTRODE ASSEMBLY, AND POLYMER ELECTROLYTE FUEL CELL EACH USING THE SAME TORAY INDUSTRIES, INC. (JP) 2017-05-04 US disclosed
US-20170095809-A1 FUNCTIONALIZED MAIN CHAIN POLYMERS HÄRING THOMAS (DE) 2017-04-06 US disclosed
US-9515341-B2 Porous membrane, electrolyte membrane including same, methods of manufacturing both, and fuel cell including at least one of the membranes SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-12-06 US disclosed
US-9484588-B2 Compound, composition including compound, composite formed therefrom, electrode using composition or composite, composite membrane using composite, and fuel cell including at least one selected from electrode and composite membrane SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-11-01 US disclosed
US-9450230-B2 Lithium-ion secondary battery including polybenzimidazole and method of manufacturing lithium-ion secondary battery TDK CORPORATION (JP) 2016-09-20 US disclosed
US-20160263534-A1 COMPATIBILIZED IMMISCIBLE POLYMER BLENDS AND MOLECULAR SIEVE MEMBRANES THEREOF THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2016-09-15 US disclosed
US-20160268609-A1 COMPOSITION, METHOD OF PREPARING THE COMPOSITION, ELECTRODE INCLUDING THE COMPOSITION, AND FUEL CELL INCLUDING THE ELECTRODE SAMSUNG ELECTRONICS CO LTD (KR) 2016-09-15 US disclosed
US-7649025-B2 Composite ion-exchange membrane TOYO BOSEKI KABUSHIKI KAISHA (JP) 2010-01-19 US disclosed
US-7615599-B2 Noncrosslinked, covalently crosslinked and/or ionically crosslinked polymer which can be used in direct methanol fuel cells; sulfonated polyetherketones and sulfonated polysulfones; acid doped polymer has high mechanical stability and a low permeability for hydrogen, oxygen and methanol HAERING THOMAS 2009-11-10 US disclosed
US-7445864-B2 Functionalized polyazoles, method for the production thereof, and use thereof BASF FUEL CELL GMBH (DE) 2008-11-04 US disclosed
US-20080090972-A1 Oligomers and Polymers Containing Sulfinate Groups, and Methods for Producing the Same KERRES JOCHEN 2008-04-17 US disclosed
US-20080003480-A1 recurring units comprising at least one benzazole group chosen among benzoxazole group and benzothiazole group; solid polymer electrolyte membrane, fuel cell SOLVAY (SOCIETE ANONYME) (BE) 2008-01-03 US disclosed
US-7288599-B2 Oligomers and polymers containing sulfinate groups, and method for producing the same KERRES JOCHEN 2007-10-30 US disclosed
US-7285325-B2 For use in electrolysis, in capacitors or in battery systems BASF FUEL CELL GMBH (DE) 2007-10-23 US disclosed
US-20070208153-A1 Functionalized Main Chain Polymers HARING THOMAS 2007-09-06 US disclosed
US-20070185305-A1 Oligomers and polymers containing sulfinate groups and method for the production thereof HARING THOMAS 2007-08-09 US disclosed
US-7202327-B2 Prepared by reducing sulfonated polymers, particularly sulfochlorinated polysulfone or PEEK resins; polymer (blend) membranes crosslinked, especially by alkylation of sulfinate groups with mono- di- or oligo functional electrophiles; fuel cells, electrolytic cells, batteries, gas separation processes HAERING THOMAS 2007-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230302441-A1 WELL DEFINED QUATERNARY AMMONIUM FUNCTIONALIZED QUATERPHENYLENE POLYMER DERIVATIVES FOR LOW AND HIGH TEMPERATURE POLYMER ELECTROLYTE MEMBRANE FUEL CELLS SCNN1B, SCNN1A, HVCN1 NPC1 4196/4885RAB9A 2225/4885MEN1 1725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.