Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL28491125 | 1.00 | ESR1 (0.30) | ESR1 | |
| Pyrophosphoric Acid SCHEMBL28491123 | 0.83 | FDPS (0.53) | ESR1 | |
| SCHEMBL34203 | 0.82 | ESR1 (0.31) | ESR1 | |
| Isopropyl Alcohol SCHEMBL28911509 | 0.79 | PKM (0.31) | — | |
| SCHEMBL29246290 | 0.79 | ESR1 (0.32) | ESR1 | |
| Tetrafluororesorcinol SCHEMBL123852 | 0.78 | ESR1 (0.30) | ESR1 | |
| SCHEMBL2923213 | 0.78 | ESR1 (0.30) | ESR1 | |
| SCHEMBL390508 | 0.78 | ESR1 (0.30) | ESR1 | |
| SCHEMBL1960786 | 0.78 | ESR1 (0.30) | ESR1 | |
| SCHEMBL3706878 | 0.78 | ESR1 (0.30) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110845560-B | Phenylalanine amidated nucleotide derivative and preparation method and application thereof | 广东中科药物研究有限公司 | 2021-08-24 | — | — | CN | claimed |
| CN-110845560-A | Phenylalanine amidated nucleotide derivative and preparation method and application thereof | 广东中科药物研究有限公司 | 2020-02-28 | — | — | CN | claimed |
| CN-119080858-A | Ribose-adenine dimer prodrug compound, preparation method and pharmaceutical application thereof | 郑州大学 | 2024-12-06 | — | — | CN | disclosed |
| CN-114288313-B | Application of pyrimidine nucleoside medicine in preparing medicine for preventing or treating coronavirus infectious diseases | 常晓宇 | 2023-07-04 | — | — | CN | disclosed |
| CN-114288313-A | Application of pyrimidine nucleoside medicament in preparing medicament for preventing or treating coronavirus infectious diseases | 常晓宇 | 2022-04-08 | — | — | CN | disclosed |
| CN-110845560-B | Phenylalanine amidated nucleotide derivative and preparation method and application thereof | 广东中科药物研究有限公司 | 2021-08-24 | — | — | CN | disclosed |
| CN-110845560-A | Phenylalanine amidated nucleotide derivative and preparation method and application thereof | 广东中科药物研究有限公司 | 2020-02-28 | — | — | CN | disclosed |
| CN-109422790-A | A kind of new preparation process of Suo Feibuwei | 常州制药厂有限公司 | 2019-03-05 | — | — | CN | disclosed |
| US-20100029008-A1 | POLYMERASE-INDEPENDENT ANALYSIS OF THE SEQUENCE OF POLYNUCLEOTIDES | FEBIT BIOTECH GMBH (DE) | 2010-02-04 | — | — | US | disclosed |
| EP-1828217-A2 | POLYMERASE-INDEPENDENT ANALYSIS OF THE SEQUENCE OF POLYNUCLEOTIDES | Febit Biotech GmbH (DE) | 2007-09-05 | — | — | EP | disclosed |
| WO-2006063717-A2 | POLYMERASE-INDEPENDENT ANALYSIS OF THE SEQUENCE OF POLYNUCLEOTIDES | FEBIT BIOTECH GMBH (DE) | 2006-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029008-A1 | POLYMERASE-INDEPENDENT ANALYSIS OF THE SEQUENCE OF POLYNUCLEOTIDES | POLB, POLM, POLN | ESR1 4580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.