SCHEMBL3488261

SCHEMBL3488261

O=c1cc(I)n([C@H]2O[C@@H](COP(=O)(O)O)C(O)C2O)c(=O)[nH]1

nearest known ligand 0.76

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
UMPS P11172 4/20 0.65
P2RY2 P41231 8/20 0.60
DNPH1 O43598 1/20 0.53
P2RY6 Q15077 7/20 0.52
P2RY4 P51582 3/20 0.51
P2RY14 Q15391 2/20 0.50
P2RX3 P56373 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1364786 1.00 UMPS (0.65) UMPSP2RY2DNPH1P2RY6P2RY4
SCHEMBL12143538 1.00 UMPS (0.65) UMPSP2RY2DNPH1P2RY6P2RY4
SCHEMBL15196265 1.00 UMPS (0.65) UMPSP2RY2DNPH1P2RY6P2RY4
SCHEMBL12143119 1.00 UMPS (0.65) UMPSP2RY2DNPH1P2RY6P2RY4
SCHEMBL16871703 0.93 UMPS (0.58) UMPSP2RY2P2RY6P2RY14
SCHEMBL30597790 0.91 P2RY2 (0.72) UMPSP2RY2P2RY6P2RY4P2RY14
Ammonia Solution, Strong SCHEMBL29559162 0.91 P2RY2 (0.71) UMPSP2RY2P2RY6P2RY4P2RY14
SCHEMBL2130675 0.87 P2RY2 (0.61) UMPSP2RY2DNPH1P2RY6P2RY4
SCHEMBL12727821 0.87 P2RY2 (0.61) UMPSP2RY2DNPH1P2RY6P2RY4
SCHEMBL3207342 0.87 P2RY2 (0.58) UMPSP2RY2DNPH1P2RY6P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100087388-A1 ODCASE INHIBITORS AS ANTI-VIRALS AND ANTIBIOTICS KOTRA LAKSHMI P 2010-04-08 US disclosed
WO-2007038860-A8 ODCASE INHIBITORS AS ANTI-VIRALS AND ANTIBIOTICS UNIV HEALTH NETWORK (CA) 2007-12-21 WO disclosed
WO-2007038860-A3 ODCASE INHIBITORS AS ANTI-VIRALS AND ANTIBIOTICS KOTRA LAKSHMI P (CA) 2007-06-07 WO disclosed
WO-2007038860-A2 ODCASE INHIBITORS AS ANTI-VIRALS AND ANTIBIOTICS UNIVERSITY HEALTH NETWORK (CA) 2007-04-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100087388-A1 ODCASE INHIBITORS AS ANTI-VIRALS AND ANTIBIOTICS ITPA, DUT, MAOA UMPS 10/4885P2RY2 4009/4885DNPH1 1002/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.