Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27761713 | 0.90 | EPHX2 (0.54) | EPHX1EPHX2RECQLKDM4EKMT2A | |
| SCHEMBL22951169 | 0.89 | EPHX1 (0.48) | EPHX1EPHX2RECQLKDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL4289843 | 0.88 | EPHX1 (0.53) | EPHX1EPHX2RECQLKDM4EKMT2A | |
| SCHEMBL3263447 | 0.83 | HTT (0.41) | KDM4EKMT2AMEN1SIGMAR1POLB | |
| SCHEMBL3487314 | 0.83 | CCR1 (0.44) | KDM4ESIGMAR1POLBCHRM1 | |
| SCHEMBL22208127 | 0.82 | POLB (0.46) | EPHX1EPHX2KDM4EKMT2AMEN1 | |
| SCHEMBL21847058 | 0.81 | ALDH1A1 (0.46) | KDM4EL3MBTL1SIGMAR1POLB | |
| SCHEMBL3488727 | 0.80 | CTSK (0.48) | EPHX1EPHX2KDM4EKMT2AMEN1 | |
| SCHEMBL13738688 | 0.80 | EPHX1 (0.44) | EPHX1EPHX2RECQLKDM4EKMT2A | |
| SCHEMBL13738686 | 0.80 | EPHX1 (0.44) | EPHX1EPHX2RECQLKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100075973-A1 | POLO-LIKE KINASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100075973-A1 | POLO-LIKE KINASE INHIBITORS | PLK2, PLK4, PLK1 | EPHX1 3095/4885EPHX2 3281/4885RECQL 605/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.