Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CCR4 | P51679 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.36 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3489152 | 0.83 | EPHX1 (0.47) | MEN1KMT2ASIGMAR1KDM4EPOLB | |
| SCHEMBL3489553 | 0.81 | CTSK (0.45) | HTTKMT2A | |
| SCHEMBL29602619 | 0.81 | PIK3CD (0.50) | PIK3CDPARP1ALDH1A1KDM4ETDP1 | |
| SCHEMBL922132 | 0.80 | SIGMAR1 (0.41) | SIGMAR1KDM4EPOLB | |
| SCHEMBL3268411 | 0.79 | PIK3CD (0.46) | HTTPIK3CDMEN1KMT2ALMNA | |
| SCHEMBL3487314 | 0.79 | CCR1 (0.44) | PARP1SIGMAR1KDM4ETDP1POLB | |
| SCHEMBL22208127 | 0.79 | POLB (0.46) | HTTMEN1KMT2ASIGMAR1ALDH1A1 | |
| SCHEMBL23560353 | 0.78 | MEN1 (0.39) | HTTPIK3CDMEN1KMT2ALMNA | |
| SCHEMBL22856079 | 0.78 | TLR9 (0.38) | HTTPIK3CDMEN1KMT2ALMNA | |
| SCHEMBL21847058 | 0.78 | ALDH1A1 (0.46) | SIGMAR1ALDH1A1KDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010025073-A1 | DIHYDROIMIDAZO [ 1, 5-F] PTERIDINES AS POLO-LIKE KINASE INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-03-04 | — | — | WO | disclosed |