Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.53 |
| ▸ | RAB9A | P51151 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TERT | O14746 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30898565 | 1.00 | MAPT (0.53) | MAPTRAB9ANPC1KDM4EMAPK1 | |
| SCHEMBL13486847 | 0.86 | MAPT (0.51) | MAPTRAB9ANPC1KDM4EMAPK1 | |
| SCHEMBL13486855 | 0.86 | MAPT (0.51) | MAPTRAB9ANPC1KDM4EMAPK1 | |
| SCHEMBL29717125 | 0.85 | KDM4E (0.55) | MAPTRAB9ANPC1KDM4EHPGD | |
| SCHEMBL2701032 | 0.85 | KDM4E (0.55) | MAPTRAB9ANPC1KDM4EHPGD | |
| SCHEMBL1177340 | 0.84 | CYP2A6 (0.47) | MAPTRAB9ANPC1KDM4EMAPK1 | |
| SCHEMBL834744 | 0.83 | CYP2A6 (0.68) | MAPTRAB9ANPC1KDM4ECYP2A6 | |
| SCHEMBL30504311 | 0.83 | LCK (0.56) | MAPTRAB9ANPC1KDM4EHPGD | |
| SCHEMBL28040989 | 0.83 | HPGD (0.48) | MAPTRAB9ANPC1KDM4EMAPK1 | |
| SCHEMBL13486851 | 0.82 | APP (0.48) | MAPTRAB9ANPC1KDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110059477-A1 | FLUORESCENT DYE-LABELED GLUCOSE BIOPROBE, SYNTHESIS METHOD AND USAGE THEREOF | SNU R&DB FOUNDATION (KR) | 2011-03-10 | — | — | US | claimed |
| US-11957766-B2 | HNQO1-activatable fluorescent probe for imaging cancer cells in-vitro and in-vivo | TEXAS TECH UNIVERSITY SYSTEM (US) | 2024-04-16 | — | — | US | disclosed |
| US-20230348884-A1 | Fluorescent Biosensor for Rapid Determination of L-arginine | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2023-11-02 | — | — | US | disclosed |
| US-20230099969-A1 | TWO-PHOTON FLUORESCENT PROBE COMPOUND SELECTIVE FOR AMYLOID BETA PLAQUES AND METHOD FOR IMAGING AMYLOID BETA PLAQUES USING SAME | KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) | 2023-03-30 | — | — | US | disclosed |
| CN-114874198-A | A beta fluorescent probe based on rhodamine-copper complex and application thereof | 黄淮学院 | 2022-08-09 | — | — | CN | disclosed |
| WO-2022078294-A1 | SUBSTITUTED HETEROARYL COMPOUNDS AND USE THEREOF | HELIOS HUAMING BIOPHARMA CO., LTD. (CN) | 2022-04-21 | — | — | WO | disclosed |
| WO-2022011508-A1 | SYSTEMS AND METHODS FOR PRESSURE MEASUREMENT | JILIN UNIVERSITY (CN) | 2022-01-20 | — | — | WO | disclosed |
| US-9896479-B2 | Functionalized naphthalene fluorophores | Kay M. Brummond (US) | 2018-02-20 | — | — | US | disclosed |
| US-20170327509-A1 | TWO-PHOTON ABSORBING FLUOROPHORES AND METHOD FOR CELLULAR IMAGING USING THE SAME | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2017-11-16 | — | — | US | disclosed |
| US-20170327509-A1 | TWO-PHOTON ABSORBING FLUOROPHORES AND METHOD FOR CELLULAR IMAGING USING THE SAME | POSTECH ACADEMY-INDUSTRY FOUNDATION (KR) | 2017-11-16 | — | — | US | disclosed |
| WO-2006023821-A2 | LIGANDS FOR ALDOKETOREDUCTASES | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2006-03-02 | — | — | WO | disclosed |
| EP-1624900-A2 | METHODS FOR BINDING AGENTS TO BETA-AMYLOID PLAQUES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-02-15 | — | — | EP | disclosed |
| WO-2005040337-A2 | METHODS FOR BINDING AGENTS TO β-AMYLOID PLAQUES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2005-05-06 | — | — | WO | disclosed |
| US-20040072371-A1 | Compositions for labeling beta-amyloid plaques and neurofibrillary tangles | REGENTS OF THE UNIVERSITY OF CALIFORNIA, THE | 2004-04-15 | — | — | US | disclosed |
| US-6660530-B2 | Diagnosis of Alzheimer's disease | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2003-12-09 | — | — | US | disclosed |
| EP-1105163-A4 | METHODS FOR LABELING BETA-AMYLOID PLAQUES AND NEUROFIBRILLARY TANGLES | UNIV CALIFORNIA (US) | 2003-05-02 | — | — | EP | disclosed |
| US-20020022002-A1 | Methods for labeling beta-amyloid plaques and neurofibrillary tangles | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-02-21 | — | — | US | disclosed |
| US-6274119-B1 | LABELING .BETA.-AMYLOID PLAQUES AND NEUROFIBRILLARY TANGLES IN VIVO AND IN VITRO, COMPRISES CONTACTING RADIOLABELED AMINONAPTHALENE DERIVATIVE WITH MAMMALIAN TISSUE | THE REGENTS OF THE UNIV. OF CALIFORNIA | 2001-08-14 | — | — | US | disclosed |
| EP-1105163-A1 | METHODS FOR LABELING BETA-AMYLOID PLAQUES AND NEUROFIBRILLARY TANGLES | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-06-13 | — | — | EP | disclosed |
| WO-2000010614-A1 | METHODS FOR LABELING β-AMYLOID PLAQUES AND NEUROFIBRILLARY TANGLES | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-03-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020022002-A1 | Methods for labeling beta-amyloid plaques and neurofibrillary tangles | OXSR1, MSR1, CBR1 | MAPT 383/4885RAB9A 3979/4885NPC1 288/4885 |
| US-20110059477-A1 | FLUORESCENT DYE-LABELED GLUCOSE BIOPROBE, SYNTHESIS METHOD AND USAGE THEREOF | OGA, UGGT1, GALE | MAPT 2604/4885RAB9A 2200/4885NPC1 917/4885 |
| US-20040072371-A1 | Compositions for labeling beta-amyloid plaques and neurofibrillary tangles | CBR1, CBR3, MSR1 | MAPT 253/4885RAB9A 3542/4885NPC1 335/4885 |
| US-20170327509-A1 | TWO-PHOTON ABSORBING FLUOROPHORES AND METHOD FOR CELLULAR IMAGING USING THE SAME | ACE2, DNPEP, ACE | MAPT 2883/4885RAB9A 1166/4885NPC1 1058/4885 |
| US-11957766-B2 | HNQO1-activatable fluorescent probe for imaging cancer cells in-vitro and in-vivo | NQO1, NQO2, NDUFA1 | MAPT 4335/4885RAB9A 1763/4885NPC1 1253/4885 |
| US-20230099969-A1 | TWO-PHOTON FLUORESCENT PROBE COMPOUND SELECTIVE FOR AMYLOID BETA PLAQUES AND METHOD FOR IMAGING AMYLOID BETA PLAQUES USING SAME | APP, BACE1, BACE2 | MAPT 25/4885RAB9A 2205/4885NPC1 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.