SCHEMBL3489535

SCHEMBL3489535

c1ccc2c(c1)CSN2

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4495963 0.76 NPC1 (0.42)
SCHEMBL4493865 0.73 MAPT (0.46)
SCHEMBL12672192 0.69 EPHX2 (0.42)
SCHEMBL449770 0.67 PLAU (0.42)
SCHEMBL30271877 0.67 ALOX15 (0.43)
SCHEMBL28751195 0.67 ALOX15 (0.39)
SCHEMBL446852 0.67 NPC1 (0.34)
SCHEMBL4505185 0.67 ALOX15 (0.43)
SCHEMBL17349231 0.66 ACHE (0.38)
SCHEMBL449771 0.65 NPC1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 165 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250313535-A1 ALPHA 4 BETA 7 INTEGRIN MODULATORS AND USES THEREOF DICE MOLECULES SV, INC. 2025-10-09 US claimed
EP-4522589-A1 ALPHA 4 BETA 7 INTEGRIN MODULATORS AND USES THEREOF Dice Molecules Sv, Inc. (US) 2025-03-19 EP claimed
CN-119562944-A Alpha 4 beta 7 integrin modulators and uses thereof 戴斯分子SV有限公司 2025-03-04 CN claimed
WO-2023220741-A1 ALPHA 4 BETA 7 INTEGRIN MODULATORS AND USES THEREOF DICE MOLECULES SV, INC. (US) 2023-11-16 WO claimed
US-7285553-B2 Serotonergic 5HT7 receptor compounds for treating ocular and CNS disorders ALCON MANUFACTURING, LTD. (US) 2007-10-23 US claimed
US-20260092053-A1 KHK INHIBITORS GILEAD SCIENCES INC (US) 2026-04-02 US disclosed
EP-4681774-A2 KHK INHIBITORS Gilead Sciences, Inc. (US) 2026-01-21 EP disclosed
EP-4665737-A1 PHOSPHOLIPID COMPOUNDS AND METHODS OF MAKING AND USING THE SAME GILEAD SCIENCES, INC. (US) 2025-12-24 EP disclosed
US-20250361236-A9 DIACYLGLYCEROL KINASE MODULATING COMPOUNDS GILEAD SCIENCES INC (US) 2025-11-27 US disclosed
EP-4313967-B1 KHK INHIBITORS GILEAD SCIENCES INC (US) 2025-11-12 EP disclosed
US-20250313535-A1 ALPHA 4 BETA 7 INTEGRIN MODULATORS AND USES THEREOF DICE MOLECULES SV, INC. 2025-10-09 US disclosed
US-12410160-B2 KHK inhibitors GILEAD SCIENCES, INC. (US) 2025-09-09 US disclosed
US-20050197362-A1 Preventives/remedies for urinary disturbance TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2005-09-08 US disclosed
US-20050053871-A1 Novel surfactants for use in substantially light-insensitive thermographic recording materials AGFA-GEVAERT N.V. (BE) 2005-03-10 US disclosed
CN-1589153-A Prevention or treatment of urinary disorders TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2005-03-02 CN disclosed
EP-1466625-A1 PREVENTIVES/REMEDIES FOR URINARY DISTURBANCE Takeda Chemical Industries, Ltd. (JP) 2004-10-13 EP disclosed
EP-1311264-A1 SUBSTITUTED AND NON-SUBSTITUTED BENZOOXATHIAZOLES AND COMPOUNDS DERIVED THEREFROM Aventis Pharma Deutschland GmbH (DE) 2003-05-21 EP disclosed
WO-2002011722-A1 SUBSTITUTED AND NON-SUBSTITUTED BENZOOXATHIAZOLES AND COMPOUNDS DERIVED THEREFROM AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2002-02-14 WO disclosed
US-4031227-A CNS DEPRESSANT AGENTS, SLEEP INDUCERS, TRANQUILIZERS SANDOZ, INC. (US) 1977-06-21 US disclosed
US-4031227-A CNS DEPRESSANT AGENTS, SLEEP INDUCERS, TRANQUILIZERS SANDOZ, INC. (US) 1977-06-21 US disclosed