SCHEMBL3489808

SCHEMBL3489808

CC1(CO)CCC[C@@]2(C)[C@H]1CC[C@]13C[C@@H](CC[C@@H]12)[C@@](C)(O)C3

nearest known ligand 0.79

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 3/20 0.79
HSD11B2 P80365 1/20 0.55
BCHE P06276 3/20 0.44
ACHE P22303 2/20 0.44
F10 P00742 3/20 0.41
CDC25B P30305 3/20 0.40
CDC25A P30304 2/20 0.40
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
PTPN1 P18031 2/20 0.37
POLB P06746 1/20 0.37
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
THRB P10828 1/20 0.36
PLA2G1B P04054 1/20 0.36
PTPN2 P17706 1/20 0.36
NR1H4 Q96RI1 1/20 0.35
SELP P16109 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3489806 1.00 HSD11B1 (0.79) HSD11B1HSD11B2BCHEACHEF10
SCHEMBL16335450 0.85 HSD11B1 (0.56) HSD11B1HSD11B2F10CDC25BMEN1
SCHEMBL30111361 0.85 HSD11B1 (0.56) HSD11B1HSD11B2F10CDC25BMEN1
SCHEMBL16335449 0.85 HSD11B1 (0.56) HSD11B1HSD11B2F10CDC25BMEN1
SCHEMBL3493335 0.85 HSD11B1 (0.56) HSD11B1HSD11B2F10CDC25BMEN1
SCHEMBL3493333 0.85 HSD11B1 (0.56) HSD11B1HSD11B2F10CDC25BMEN1
SCHEMBL14510816 0.84 HSD11B1 (0.60) HSD11B1HSD11B2BCHEACHEF10
SCHEMBL3490070 0.80 HSD11B1 (0.65) HSD11B1HSD11B2BCHEACHEF10
SCHEMBL3490073 0.80 HSD11B1 (0.65) HSD11B1HSD11B2BCHEACHEF10
Annosquamosin B SCHEMBL31497491 0.80 HSD11B1 (0.81) HSD11B1HSD11B2BCHEACHEF10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170055532-A1 SYSTEMS FOR PEST ELIMINATION, SUPPRESSION OR CONTROL Emekatech, LLC. (US) 2017-03-02 US claimed
EP-3110253-A1 SYSTEMS FOR PEST ELIMINATION, SUPPRESSION OR CONTROL Emekatech, LLC (US) 2017-01-04 EP claimed
WO-2015127311-A1 SYSTEMS FOR PEST ELIMINATION, SUPPRESSION OR CONTROL EMEKATECH, LLC (US) 2015-08-27 WO claimed
EP-2155769-B1 TISSUE DEGENERATION PROTECTION UNIV LEUVEN KATH (BE) 2012-06-27 EP claimed
US-20100099640-A1 TISSUE DEGENERATION PROTECTION GEUNS JOANNES 2010-04-22 US claimed
US-20200093135-A1 SYSTEMS FOR PEST ELIMINATION, SUPPRESSION OR CONTROL EMEKATECH LLC (US) 2020-03-26 US disclosed
US-20170055532-A1 SYSTEMS FOR PEST ELIMINATION, SUPPRESSION OR CONTROL Emekatech, LLC. (US) 2017-03-02 US disclosed
EP-3110253-A1 SYSTEMS FOR PEST ELIMINATION, SUPPRESSION OR CONTROL Emekatech, LLC (US) 2017-01-04 EP disclosed
WO-2015127311-A1 SYSTEMS FOR PEST ELIMINATION, SUPPRESSION OR CONTROL EMEKATECH, LLC (US) 2015-08-27 WO disclosed
EP-2155769-B1 TISSUE DEGENERATION PROTECTION UNIV LEUVEN KATH (BE) 2012-06-27 EP disclosed
US-20100099640-A1 TISSUE DEGENERATION PROTECTION GEUNS JOANNES 2010-04-22 US disclosed
EP-2155769-A2 TISSUE DEGENERATION PROTECTION Katholieke Universiteit Leuven (BE) 2010-02-24 EP disclosed
WO-2008134828-A2 TISSUE DEGENERATION PROTECTION KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2008-11-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099640-A1 TISSUE DEGENERATION PROTECTION SORD, CASP3, TXNRD2 HSD11B1 187/4885HSD11B2 114/4885BCHE 3941/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.