Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5838819 | 1.00 | USP2 (0.38) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL30320761 | 1.00 | USP2 (0.38) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL5838959 | 1.00 | USP2 (0.38) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL565381 | 0.91 | USP2 (0.43) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL5837970 | 0.89 | ALDH1A1 (0.31) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL5839404 | 0.89 | ALDH1A1 (0.31) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL5838833 | 0.89 | ALDH1A1 (0.31) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL5837856 | 0.89 | ALDH1A1 (0.31) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL564550 | 0.80 | TSHR (0.52) | USP2TSHRKDM4EALDH1A1LMNA | |
| SCHEMBL563993 | 0.80 | TSHR (0.60) | USP2TSHRKDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100029568-A1 | TIGHTER-BINDING C-PEPTIDE INHIBITORS OF HIV-1 ENTRY | THOMAS JEFFERSON UNIVERSITY (US) | 2010-02-04 | — | — | US | disclosed |
| EP-2125876-A1 | TIGHTER-BINDING C-PEPTIDE INHIBITORS OF HIV-1 ENTRY | THOMAS JEFFERSON UNIVERSITY (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008112736-A1 | TIGHTER-BINDING C-PEPTIDE INHIBITORS OF HIV-1 ENTRY | THOMAS JEFFERSON UNIVERSITY (US) | 2008-09-18 | — | — | WO | disclosed |