Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.44 |
| ▸ | F10 | P00742 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.36 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
| ▸ | CDC25B | P30305 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3490504 | 1.00 | HSD11B1 (0.44) | HSD11B1F10MEN1KMT2ACYP19A1 | |
| SCHEMBL13401496 | 1.00 | HSD11B1 (0.44) | HSD11B1F10MEN1KMT2ACYP19A1 | |
| SCHEMBL13401639 | 0.82 | F10 (0.64) | HSD11B1F10MEN1KMT2APOLB | |
| SCHEMBL13401677 | 0.82 | F10 (0.64) | HSD11B1F10MEN1KMT2APOLB | |
| SCHEMBL13401670 | 0.79 | MEN1 (0.66) | HSD11B1F10MEN1KMT2APOLB | |
| SCHEMBL16335449 | 0.77 | HSD11B1 (0.56) | HSD11B1F10MEN1KMT2ACYP19A1 | |
| SCHEMBL3493333 | 0.77 | HSD11B1 (0.56) | HSD11B1F10MEN1KMT2ACYP19A1 | |
| SCHEMBL30111361 | 0.77 | HSD11B1 (0.56) | HSD11B1F10MEN1KMT2ACYP19A1 | |
| SCHEMBL3493335 | 0.77 | HSD11B1 (0.56) | HSD11B1F10MEN1KMT2ACYP19A1 | |
| SCHEMBL16335450 | 0.77 | HSD11B1 (0.56) | HSD11B1F10MEN1KMT2ACYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099640-A1 | TISSUE DEGENERATION PROTECTION | GEUNS JOANNES | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099640-A1 | TISSUE DEGENERATION PROTECTION | SORD, CASP3, TXNRD2 | HSD11B1 187/4885F10 551/4885MEN1 3683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.