Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3490658 | 0.98 | GAA (0.43) | GAASIRT2LMNAALDH1A1HSD17B10 | |
| SCHEMBL2233403 | 0.89 | SIRT2 (0.40) | GAASIRT2SMN1; SMN2OPRM1OPRL1 | |
| SCHEMBL11775068 | 0.87 | SIRT2 (0.42) | GAASIRT2LMNAALDH1A1HSD17B10 | |
| SCHEMBL11607014 | 0.87 | SIRT2 (0.42) | GAASIRT2LMNAALDH1A1HSD17B10 | |
| SCHEMBL8413376 | 0.87 | SIRT2 (0.42) | GAASIRT2LMNAALDH1A1HSD17B10 | |
| SCHEMBL11773588 | 0.87 | SIRT2 (0.42) | GAASIRT2LMNAALDH1A1HSD17B10 | |
| SCHEMBL11779345 | 0.87 | SIRT2 (0.42) | GAASIRT2LMNAALDH1A1HSD17B10 | |
| SCHEMBL5805215 | 0.85 | GAA (0.39) | GAASIRT2 | |
| SCHEMBL19066498 | 0.84 | SIRT2 (0.36) | SIRT2KMT2A | |
| SCHEMBL2807710 | 0.84 | TSHR (0.41) | GAASIRT2SMN1; SMN2LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090312558-A1 | PROCESS FOR THE PREPARATION OF ARYLCYCLOPROPOANE CARBOXYLIC CARBONITRILES, AND COMPOUNDS DERIVED THEREFROM | RELIANCE LIFE SCIENCES PVT. LTD. (IN) | 2009-12-17 | — | — | US | claimed |
| WO-2009150660-A1 | A PROCESS FOR THE PREPARATION OF ARYLCYCLOPROPANE CARBOXYLIC CARBONITRILES, AND COMPOUNDS DERIVED THEREFROM | RELIANCE LIFE SCIENCES PVT. LTD. (IN) | 2009-12-17 | — | — | WO | claimed |
| JP-3141233-A | — | — | None | — | — | JP | disclosed |
| JP-6271484-A | — | — | None | — | — | JP | disclosed |
| US-20090312558-A1 | PROCESS FOR THE PREPARATION OF ARYLCYCLOPROPOANE CARBOXYLIC CARBONITRILES, AND COMPOUNDS DERIVED THEREFROM | RELIANCE LIFE SCIENCES PVT. LTD. (IN) | 2009-12-17 | — | — | US | disclosed |
| WO-2009150660-A1 | A PROCESS FOR THE PREPARATION OF ARYLCYCLOPROPANE CARBOXYLIC CARBONITRILES, AND COMPOUNDS DERIVED THEREFROM | RELIANCE LIFE SCIENCES PVT. LTD. (IN) | 2009-12-17 | — | — | WO | disclosed |
| WO-2005034837-A2 | 7H-IMIDAZO [1,2-α] PYRAZIN-8-ONE COMPOUNDS AS ION CHANNEL MODULATORS | CARDIOME PHARMA CORPORATION (US) | 2005-04-21 | — | — | WO | disclosed |
| JP-H06271484-A | PRODUCTION OF DIHYDRONAPHTHALENES | SUMITOMO CHEM CO LTD | 1994-09-27 | — | — | JP | disclosed |
| JP-H03141233-A | HALONAPHTHALENE DERIVATIVE, PREPARATION AND INTERMEDIATE THEREOF | SUMITOMO CHEM CO LTD | 1991-06-17 | — | — | JP | disclosed |
| US-4554095-A | PERFUMES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1985-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312558-A1 | PROCESS FOR THE PREPARATION OF ARYLCYCLOPROPOANE CARBOXYLIC CARBONITRILES, AND COMPOUNDS DERIVED THEREFROM | NOTUM, SULT2A1, SULT1A1 | GAA 3617/4885SIRT2 3668/4885SMN1; SMN2 3522/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.