SCHEMBL349079

SCHEMBL349079

CC(N)CC[PH](=O)O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8422592 0.85
SCHEMBL5082326 0.85
Hydrochloric Acid SCHEMBL10590969 0.83 ALDH1A1 (0.43)
Ammonia Solution, Strong SCHEMBL3111004 0.83 ALDH1A1 (0.43)
SCHEMBL601259 0.78
SCHEMBL23429877 0.75 ALDH1A1 (0.40)
SCHEMBL2393781 0.75
SCHEMBL6028302 0.75
SCHEMBL7196855 0.75
SCHEMBL2954813 0.75 BHMT (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002100871-A1 NEW COMPOUNDS USEFUL IN REFLUX DISEASE ASTRAZENECA AB (SE) 2002-12-19 WO claimed
US-9993490-B2 Phosphonic acid compounds and screening method THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2018-06-12 US disclosed
US-20170202863-A1 PHOSPHONIC ACID COMPOUNDS AND SCREENING METHOD THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2017-07-20 US disclosed
US-20120016021-A1 METHODS OF TREATING FRAGILE X SYNDROME, DOWN'S SYNDROME, AUTISM AND RELATED DISORDERS XENOPORT, INC. (US) 2012-01-19 US disclosed
WO-2012009646-A1 METHODS OF TREATING FRAGILE X SYNDROME, DOWN'S SYNDROME, AUTISM AND RELATED DISORDERS XENOPORT, INC. (US) 2012-01-19 WO disclosed
US-20050163841-A1 Compositions and dosage forms for enhanced absorption of 3-amino-n-butyl-phosphinic acid ALZA CORPORATION 2005-07-28 US disclosed
WO-2002100871-A1 NEW COMPOUNDS USEFUL IN REFLUX DISEASE ASTRAZENECA AB (SE) 2002-12-19 WO disclosed