⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6025051 | 0.80 | CPB2 (0.31) | — | |
| SCHEMBL16974378 | 0.78 | — | — | |
| SCHEMBL23429877 | 0.76 | ALDH1A1 (0.40) | — | |
| SCHEMBL20575074 | 0.76 | — | — | |
| SCHEMBL2954813 | 0.76 | BHMT (0.32) | — | |
| SCHEMBL349079 | 0.75 | — | — | |
| SCHEMBL351642 | 0.75 | — | — | |
| SCHEMBL2949069 | 0.74 | BHMT (0.31) | — | |
| SCHEMBL601259 | 0.74 | — | — | |
| SCHEMBL1890963 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2884985-A1 | TOPICAL SKIN CARE COMPOSITION | Jafer Limited (VG) | 2015-06-24 | — | — | EP | claimed |
| WO-2014028032-A1 | TOPICAL SKIN CARE COMPOSITION | JAFER LIMITED (VG) | 2014-02-20 | — | — | WO | claimed |
| EP-2884985-A1 | TOPICAL SKIN CARE COMPOSITION | Jafer Limited (VG) | 2015-06-24 | — | — | EP | disclosed |
| WO-2014028032-A1 | TOPICAL SKIN CARE COMPOSITION | JAFER LIMITED (VG) | 2014-02-20 | — | — | WO | disclosed |
| EP-1685142-A1 | PHOSPHINIC ACID DERIVATIVES, BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 2006-08-02 | — | — | EP | disclosed |
| WO-2005044830-A1 | PHOSPHINIC ACIDS DERIVATIVES, BETA-SECRETASE INHIBITORS FOR THE TREATMENT OF ALZHEIMER’S DISEASE | F. HOFFMANN-LA ROCHE AG (CH) | 2005-05-19 | — | — | WO | disclosed |