Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 6/20 | 0.35 |
| ▸ | MMP3 | P08254 | 6/20 | 0.35 |
| ▸ | MMP1 | P03956 | 3/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | Q9HBH1 | 1/20 | 0.35 | |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | BHMT | Q93088 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30350403 | 0.85 | SLC7A5 (0.48) | ALDH1A1MAPTPTGS1MMP3MMP1 | |
| SCHEMBL29666118 | 0.85 | PTGS1 (0.45) | ALDH1A1MAPTPTGS1MMP2MMP1 | |
| SCHEMBL29378289 | 0.85 | PTGS1 (0.42) | ALDH1A1MAPTPTGS1OPRM1DPP4 | |
| SCHEMBL31091497 | 0.84 | DPP4 (0.53) | ALDH1A1MAPTPTGS1DPP4DPP8 | |
| SCHEMBL31222374 | 0.83 | PTGS1 (0.41) | ALDH1A1MAPTPTGS1OPRM1DPP4 | |
| SCHEMBL31680489 | 0.82 | PTGS1 (0.40) | ALDH1A1MAPTPTGS1OPRM1DPP4 | |
| SCHEMBL30350525 | 0.81 | SLC1A3 (0.40) | ALDH1A1MAPTPTGS1MMP3MMP1 | |
| SCHEMBL29378707 | 0.80 | DPP8 (0.51) | ALDH1A1MAPTPTGS1OPRM1DPP4 | |
| SCHEMBL31258939 | 0.80 | DPP7 (0.47) | ALDH1A1MAPTPTGS1MMP2DPP4 | |
| SCHEMBL29376144 | 0.79 | ALDH1A1 (0.57) | ALDH1A1MAPTPTGS1OPRM1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099640-A1 | TISSUE DEGENERATION PROTECTION | GEUNS JOANNES | 2010-04-22 | — | — | US | disclosed |
| US-7371721-B2 | Use of GLP-2 and related compounds for the treatment, prevention, diagnosis, and prognosis of bone-related disorders and calcium homeostasis related syndromes | SANOS BIOSCIENCE A/S (DK) | 2008-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099640-A1 | TISSUE DEGENERATION PROTECTION | SORD, CASP3, TXNRD2 | ALDH1A1 325/4885MAPT 1418/4885PTGS1 103/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.