SCHEMBL3491867

SCHEMBL3491867

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nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AHCY P23526 2/20 0.32
GBA1 P04062 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4270346 1.00 AHCY (0.32) AHCYGBA1
SCHEMBL15895258 1.00 AHCY (0.32) AHCYGBA1
SCHEMBL8616449 1.00 AHCY (0.32) AHCYGBA1
SCHEMBL9344785 1.00 AHCY (0.32) AHCYGBA1
SCHEMBL15894566 1.00 AHCY (0.32) AHCYGBA1
SCHEMBL25144059 1.00 AHCY (0.32) AHCYGBA1
SCHEMBL7151061 0.97 AHCY (0.33) AHCY
SCHEMBL22188727 0.97 AHCY (0.33) AHCY
SCHEMBL10952939 0.97 AHCY (0.33) AHCY
SCHEMBL4862232 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2155769-B1 TISSUE DEGENERATION PROTECTION UNIV LEUVEN KATH (BE) 2012-06-27 EP claimed
US-20100099640-A1 TISSUE DEGENERATION PROTECTION GEUNS JOANNES 2010-04-22 US claimed
EP-2155769-A2 TISSUE DEGENERATION PROTECTION Katholieke Universiteit Leuven (BE) 2010-02-24 EP claimed
WO-2008134828-A2 TISSUE DEGENERATION PROTECTION KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2008-11-13 WO claimed
EP-2155769-B1 TISSUE DEGENERATION PROTECTION UNIV LEUVEN KATH (BE) 2012-06-27 EP disclosed
US-20100099640-A1 TISSUE DEGENERATION PROTECTION GEUNS JOANNES 2010-04-22 US disclosed
EP-2155769-A2 TISSUE DEGENERATION PROTECTION Katholieke Universiteit Leuven (BE) 2010-02-24 EP disclosed
WO-2008134828-A2 TISSUE DEGENERATION PROTECTION KATHOLIEKE UNIVERSITEIT LEUVEN (BE) 2008-11-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100099640-A1 TISSUE DEGENERATION PROTECTION SORD, CASP3, TXNRD2 AHCY 4628/4885GBA1 613/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.