SCHEMBL3492

SCHEMBL3492

CC(=O)c1ccc(Cl)s1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2872059 0.82 GSK3B (0.67)
SCHEMBL9144815 0.80 F2 (0.70)
SCHEMBL23074375 0.79 F2 (0.55)
SCHEMBL76028 0.78
SCHEMBL15525171 0.78
SCHEMBL1770739 0.78
SCHEMBL17088064 0.78
SCHEMBL3745752 0.78
SCHEMBL92875 0.78
SCHEMBL77196 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 392 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117486872-A Mechanical ball milling synthesis method of aminothiazole compound 浙江工业大学 2024-02-02 CN claimed
WO-2019142208-A1 AMBIENT TEMPERATURE CURABLE NON-ISOCYANATE POLYHYDROXYALKYLURETHANE MOIETIES WITH ALDEHYDE CROSS LINKER Asian Paints Ltd. (IN) 2019-07-25 WO claimed
US-8436013-B2 Compounds and methods for treatment of alpha-1 antitrypsin deficiency UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2013-05-07 US claimed
CN-102993164-A Preparation method for 2-chlorine-5-thiophene formic acid LIANYUNGANG HONGYE CHEMICAL CO LTD 2013-03-27 CN claimed
US-20100076018-A1 Compounds and Methods for Treatment of Alpha-1 Antitrypsin Deficiency UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2010-03-25 US claimed
EP-2114141-A2 COMPOUNDS AND METHODS FOR TREATMENT OF ALPHA-1 ANTITRYPSIN DEFICIENCY University of Florida (US) 2009-11-11 EP claimed
WO-2008143633-A2 COMPOUNDS AND METHODS FOR TREATMENT OF ALPHA-1 ANTITRYPSIN DEFICIENCY UNIVERSITY OF FLORIDA (US) 2008-11-27 WO claimed
US-6096124-A Ink compositions XEROX CORPORATION (US) 2000-08-01 US claimed
US-5665504-A Simulated photographic-quality prints using a plasticizer to reduce curl XEROX CORPORATION (US) 1997-09-09 US claimed
JP-61152677-A None JP disclosed
US-20260055062-A1 HETEROCYCLIC INHIBITORS OF MCT4 Vettore, LLC 2026-02-26 US disclosed
US-12522618-B2 Copper complexes for treatment of neurodegenerative disorders ALS THERAPY DEVELOPMENT INSTITUTE (US) 2026-01-13 US disclosed
US-12492171-B2 Heterocyclic inhibitors of MCT4 Vettore, LLC (US) 2025-12-09 US disclosed
US-20250243177-A1 sGC STIMULATORS CYCLERION THERAPEUTICS, INC. 2025-07-31 US disclosed
US-4160838-A FUNGICIDES, BACTERICIDES JANSSEN PHARMACEUTICA N.V. (BE) 1979-07-10 US disclosed
US-4105663-A HYPOTENSIVE, BLOCKING AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1978-08-08 US disclosed
US-4093628-A HYPOTENSIVE AGENTS, BLOCKING AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1978-06-06 US disclosed
US-4082772-A HYPOTENSIVE AGENTS, B-ADRENERGIC BLOCKING AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1978-04-04 US disclosed
US-4079062-A ANTIMICROBIAL, PLANT GROWTH REGULATORS; 1-(B-ARYL)ETHYL-1H-1,2,4-TRIAZOLE KETALS JANSSEN PHARMACEUTICA N.V. (BE) 1978-03-14 US disclosed
US-4024156-A Thiophene ethanolamines AMERICAN HOME PRODUCTS CORPORATION (US) 1977-05-17 US disclosed