SCHEMBL3493347

SCHEMBL3493347

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nearest known ligand 0.59

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
TDP1 Q9NUW8 2/20 0.56
KDM4E B2RXH2 2/20 0.40
PDE4A P27815 1/20 0.40
USP2 O75604 1/20 0.37
SLCO1B1 Q9Y6L6 1/20 0.37
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1270185 0.80 LMNA (0.47) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL20594083 0.75 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL20567656 0.75 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL13187369 0.75 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Adonitol SCHEMBL22572531 0.75 LMNA (0.83) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL23066399 0.75 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Xylitol SCHEMBL20594034 0.75 LMNA (0.83) LMNAL3MBTL1TDP1KDM4EPDE4A
Adonitol SCHEMBL20594035 0.75 LMNA (0.83) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL21837180 0.75 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A
Mannitol SCHEMBL20594082 0.75 LMNA (1.00) LMNAL3MBTL1TDP1KDM4EPDE4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100129385-A1 IMMUNOGENIC MOLECULES COUNCIL OF THE QUEENSLAND INSTITUTE OF MEDICAL RESEARCH, THE (AU) 2010-05-27 US disclosed
EP-1861426-A4 IMMUNOGENIC MOLECULES QUEENSLAND INST MED RES (AU) 2008-11-12 EP disclosed
EP-1861426-A1 IMMUNOGENIC MOLECULES THE COUNCIL OF THE QUEENSLAND INSTITUTE OF MEDICAL RESEARCH (AU) 2007-12-05 EP disclosed
CN-1959378-A Albumin combination mensuration reagent of ischemia modification YIKANG TECH DEV CO LTD CHANGSH (CN) 2007-05-09 CN disclosed
CN-1959377-A Albumin combination mensuration reagent of ischemia modification, and method of application YIKANG TECH DEV CO LTD CHANGSH (CN) 2007-05-09 CN disclosed
WO-2006084319-A1 IMMUNOGENIC MOLECULES THE COUNCIL OF THE QUEENSLAND INSTITUTE OF MEDICAL RESEARCH (AU) 2006-08-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100129385-A1 IMMUNOGENIC MOLECULES HLA-DRB1, HLA-C, CD74 LMNA 4700/4885L3MBTL1 4021/4885TDP1 4277/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.