SCHEMBL349452

SCHEMBL349452

O=C1c2ccccc2C(=O)C1c1ccc2ccccc2n1.c1ccc(C(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 9/20 0.79
RAB9A P51151 9/20 0.79
MAPT P10636 7/20 0.79
SMN1; SMN2 Q16637 7/20 0.79
KMT2A Q03164 6/20 0.79
MEN1 O00255 5/20 0.79
ALDH1A1 P00352 4/20 0.79
TP53 P04637 4/20 0.79
CYP3A4 P08684 2/20 0.79
MAPK1 P28482 2/20 0.79
HIF1A Q16665 1/20 0.79
ESR1 P03372 1/20 0.57
LMNA P02545 3/20 0.40
CYP1A2 P05177 2/20 0.40
HTR2B P41595 1/20 0.40
POLB P06746 2/20 0.38
PTK2B Q14289 1/20 0.37
ADORA3 P0DMS8 1/20 0.36
THRB P10828 1/20 0.36
CHRM1 P11229 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21817022 0.89 RAB9A (1.00) NPC1RAB9AMAPTSMN1; SMN2KMT2A
SCHEMBL42716 0.89 RAB9A (1.00) NPC1RAB9AMAPTSMN1; SMN2KMT2A
SCHEMBL29350835 0.89 RAB9A (1.00) NPC1RAB9AMAPTSMN1; SMN2KMT2A
Methane SCHEMBL725576 0.88 RAB9A (0.96) NPC1RAB9AMAPTSMN1; SMN2KMT2A
SCHEMBL7791036 0.88 RAB9A (0.96) NPC1RAB9AMAPTSMN1; SMN2KMT2A
SCHEMBL9513625 0.88 RAB9A (0.96) NPC1RAB9AMAPTSMN1; SMN2KMT2A
Bicarbonate SCHEMBL7756326 0.86 RAB9A (0.87) NPC1RAB9AMAPTSMN1; SMN2KMT2A
Ethyne SCHEMBL6237008 0.86 RAB9A (0.93) NPC1RAB9AMAPTSMN1; SMN2KMT2A
Cyanide SCHEMBL8518292 0.84 RAB9A (0.90) NPC1RAB9AMAPTSMN1; SMN2KMT2A
Phthalimide SCHEMBL5678400 0.81 MAPT (0.82) NPC1RAB9AMAPTSMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240010845-A1 ACOUSTICAL BONDING OF EFFECT PIGMENTS PPG INDUSTRIES OHIO, INC. (US) 2024-01-11 US disclosed
EP-3569668-B1 POWDER COATING MATERIAL, METHOD FOR PRODUCING SUBSTRATE WITH COATING FILM, COATED ARTICLE AND FLUORINE-CONTAINING POLYMER AGC INC (JP) 2023-08-09 EP disclosed
EP-4217427-A1 ACOUSTICAL BONDING OF EFFECT PIGMENTS PPG Industries Ohio Inc. (US) 2023-08-02 EP disclosed
CN-116234880-A Acoustic bonding of effect pigments PPG工业俄亥俄公司 2023-06-06 CN disclosed
WO-2022066940-A1 ACOUSTICAL BONDING OF EFFECT PIGMENTS PPG INDUSTRIES OHIO, INC. (US) 2022-03-31 WO disclosed
US-11130870-B2 Powder coating material, method for producing substrate provided with coating film, coated article and fluorinated polymer AGC Inc. (JP) 2021-09-28 US disclosed
US-11077037-B2 Stable cosmetic composition containing a monoglyceride, a tartaric ester of monoglyceride, and a coated filler L'OREAL (FR) 2021-08-03 US disclosed
CN-112262185-A Powder coating material, method for producing same, method for producing substrate with coating film, and coated article AGC株式会社 2021-01-22 CN disclosed
EP-3401374-B1 POWDER COATING MATERIAL, METHOD FOR PRODUCING POWDER COATING MATERIAL, AND COATED ARTICLE AGC INC (JP) 2020-09-02 EP disclosed
US-10655022-B2 Powder coating material, method for producing powder coating material, and coated article AGC Inc. (JP) 2020-05-19 US disclosed
EP-1566419-B1 POWDER COATING COMPOSITION TOYO ALUMINIUM KK (JP) 2007-08-22 EP disclosed
US-20060287412-A1 Flake pigment having film containing charge regulating agent, powder metallic paint containing it, coating using it, and process for producing flake pigment TOYO ALUMINIUM KABUSHIKI KAISHA (JP) 2006-12-21 US disclosed
US-20060173113-A1 Powder coating composition and coating method of aluminum wheel NIPPON PAINT CO., LTD. (JP) 2006-08-03 US disclosed
EP-1666545-A1 FLAKE PIGMENT HAVING FILM CONTAINING CHARGE REGULATING AGENT, POWDER METALLIC PAINT CONTAINING IT, COATING USING IT AND PROCESS FOR PRODUCING FLAKE PIGMENT TOYO ALUMINIUM KABUSHIKI KAISHA (JP) 2006-06-07 EP disclosed
EP-1655349-A1 FLAKE PIGMENT, COATING MATERIAL AND POWDER COATING COMPOSITION EACH CONTAINING THE SAME, AND SURFACE-TREATING AGENT FOR FLAKY PARTICLE FOR USE THEREIN Toyo Aluminium Co., Ltd. (JP) 2006-05-10 EP disclosed
US-20060063004-A1 Flake pigment, coating material and powder coating composition each containing the same and surface-treating agent for flaky particle for use therein TOYO ALUMINIUM KABUSHIKI KAISHA (JP) 2006-03-23 US disclosed
US-20060014858-A1 Powder coating composition TOYO ALUMINIUM KABUSHIKI KAISHA (JP) 2006-01-19 US disclosed
EP-1566419-A1 POWDER COATING COMPOSITION TOYO ALUMINIUM KABUSHIKI KAISHA (JP) 2005-08-24 EP disclosed
EP-1445290-A1 POWDER COATING COMPOSITION, PROCESS FOR PRODUCING THE SAME, AND COATING FILM MADE FROM THE SAME TOYO ALUMINIUM KABUSHIKI KAISHA (JP) 2004-08-11 EP disclosed
US-20040151940-A1 Powder coating compositon, process for producing the same, and coating film made from the same TOYO ALUMINIUM KABUSHIKI KAISHA (JP) 2004-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11077037-B2 Stable cosmetic composition containing a monoglyceride, a tartaric ester of monoglyceride, and a coated filler MGLL, DAGLA, GLA NPC1 1694/4885RAB9A 2007/4885MAPT 408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.