Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.63 |
| ▸ | FYN | P06241 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8439596 | 0.98 | LCK (0.61) | LCKFYNKMT2AMEN1TP53 | |
| SCHEMBL4360179 | 0.88 | CYP3A4 (0.47) | LCKFYNKMT2AMEN1TP53 | |
| SCHEMBL4360176 | 0.86 | CYP3A4 (0.46) | LCKFYNKMT2AMEN1TP53 | |
| SCHEMBL8439600 | 0.85 | CA2 (0.49) | LCKFYNKMT2AMEN1TP53 | |
| SCHEMBL1172249 | 0.85 | TP53 (0.49) | LCKFYNKMT2AMEN1TP53 | |
| SCHEMBL11228135 | 0.83 | GAA (0.52) | KMT2AMEN1TDP1CYP3A4SMN1; SMN2 | |
| SCHEMBL668513 | 0.83 | CYP19A1 (0.52) | KMT2AMEN1TDP1CYP3A4SMN1; SMN2 | |
| SCHEMBL28543490 | 0.81 | GAA (0.50) | KMT2AMEN1TDP1CYP3A4SMN1; SMN2 | |
| SCHEMBL11221366 | 0.81 | GAA (0.50) | KMT2AMEN1TDP1CYP3A4SMN1; SMN2 | |
| SCHEMBL132541 | 0.81 | CYP3A4 (0.65) | KMT2AMEN1TP53TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-215102081-U | Treatment system containing nitric acid system | 山东友道化学有限公司 | 2021-12-10 | — | — | CN | disclosed |
| CN-212450641-U | Nitric acid treatment device containing high-boiling point organic matter | 山东友道化学有限公司 | 2021-02-02 | — | — | CN | disclosed |
| CN-111792631-A | Device and method for treating nitric acid containing high-boiling-point organic matters | 山东友道化学有限公司 | 2020-10-20 | — | — | CN | disclosed |
| CN-111620397-A | Treatment system and treatment method for nitric acid-containing system | 山东友道化学有限公司 | 2020-09-04 | — | — | CN | disclosed |
| US-7851606-B2 | Negatively charged minor groove binders | ELITECH HOLDING B.V. (NL) | 2010-12-14 | — | — | US | disclosed |
| US-20100137614-A1 | NEGATIVELY CHARGED MINOR GROOVE BINDERS | EPOCH BIOSCIENCES, INC. (US) | 2010-06-03 | — | — | US | disclosed |
| US-7582739-B2 | Negatively charged minor groove binders | EPOCH BIOSCIENCES, INC. (US) | 2009-09-01 | — | — | US | disclosed |
| US-20050187383-A1 | Negatively charged minor groove binders | LUKHTANOV, EUGENE | 2005-08-25 | — | — | US | disclosed |
| WO-2003078450-A2 | NEGATIVELY CHARGED MINOR GROOVE BINDERS | EPOCH BIOSCIENCES, INC. (US) | 2003-09-25 | — | — | WO | disclosed |
| EP-0578148-B1 | Biologically recognising layers on solid phases and method for producing same | HOFFMANN LA ROCHE (CH) | 2000-04-19 | — | — | EP | disclosed |
| EP-0578148-A2 | Biologically recognising layers on solid phases and method for producing same | F. HOFFMANN-LA ROCHE AG (CH) | 1994-01-12 | — | — | EP | disclosed |
| US-4642240-A | LOW CALORIE SWEETENERS | GENERAL FOODS CORPORATION (US) | 1987-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187383-A1 | Negatively charged minor groove binders | PCNA, NCL, HNRNPH3 | LCK 2301/4885FYN 2825/4885KMT2A 1372/4885 |
| US-20100137614-A1 | NEGATIVELY CHARGED MINOR GROOVE BINDERS | PCNA, NCL, HNRNPH3 | LCK 2301/4885FYN 2825/4885KMT2A 1372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.