Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.61 |
| ▸ | FYN | P06241 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.41 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.41 |
| ▸ | CASP6 | P55212 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3495478 | 0.98 | LCK (0.63) | LCKFYNKMT2AMEN1TP53 | |
| SCHEMBL4360176 | 0.88 | CYP3A4 (0.46) | LCKFYNKMT2AMEN1TP53 | |
| SCHEMBL4360179 | 0.86 | CYP3A4 (0.47) | LCKFYNKMT2AMEN1TP53 | |
| SCHEMBL28543490 | 0.84 | GAA (0.50) | KMT2AMEN1TDP1CYP3A4SMN1; SMN2 | |
| SCHEMBL11221366 | 0.84 | GAA (0.50) | KMT2AMEN1TDP1CYP3A4SMN1; SMN2 | |
| SCHEMBL8439600 | 0.83 | CA2 (0.49) | LCKFYNKMT2AMEN1TP53 | |
| SCHEMBL1172249 | 0.83 | TP53 (0.49) | LCKFYNKMT2AMEN1TP53 | |
| SCHEMBL11228135 | 0.82 | GAA (0.52) | KMT2AMEN1TDP1CYP3A4SMN1; SMN2 | |
| SCHEMBL668513 | 0.82 | CYP19A1 (0.52) | KMT2AMEN1TDP1CYP3A4SMN1; SMN2 | |
| SCHEMBL28117879 | 0.82 | TP53 (0.62) | KMT2AMEN1TP53TDP1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5986066-A | BIOMOLECULAR COATING ON SURFACE FOR ANALYZING SENSORY LAYERS SENSORY LAYERS | ROCHE DIAGNOSTICS CORPORATION (US) | 1999-11-16 | — | — | US | disclosed |