SCHEMBL4360179

SCHEMBL4360179

O=C(c1cc([N+](=O)[O-])cc(S(=O)(=O)O)c1)c1cc([N+](=O)[O-])cc(S(=O)(=O)O)c1.[Na]

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
LCK P06239 1/20 0.46
FYN P06241 1/20 0.46
CA1 P00915 3/20 0.44
CA2 P00918 3/20 0.44
CA12 O43570 2/20 0.44
CA9 Q16790 2/20 0.44
CA14 Q9ULX7 2/20 0.44
GAA P10253 3/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
NSD2 O96028 1/20 0.44
PLCG1 P19174 1/20 0.44
DNMT1 P26358 1/20 0.44
CASP6 P55212 1/20 0.44
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
HTT P42858 1/20 0.41
SRD5A2 P31213 1/20 0.41
CES2 O00748 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4360176 0.98 CYP3A4 (0.46) CYP3A4SMN1; SMN2LCKFYNCA1
SCHEMBL14421292 0.89 CES2 (0.55) CA1CA2CA12CA9CA14
SCHEMBL3495478 0.88 LCK (0.63) CYP3A4SMN1; SMN2LCKFYNCA1
SCHEMBL8439596 0.86 LCK (0.61) CYP3A4SMN1; SMN2LCKFYNGAA
SCHEMBL8439600 0.86 CA2 (0.49) CYP3A4SMN1; SMN2LCKFYNCA1
SCHEMBL11228135 0.85 GAA (0.52) CYP3A4SMN1; SMN2CA1CA2CA12
SCHEMBL668513 0.85 CYP19A1 (0.52) CYP3A4SMN1; SMN2CA1CA2CA12
SCHEMBL4360178 0.84 CYP3A4 (0.46) CYP3A4SMN1; SMN2CA1CA2CA12
SCHEMBL11221366 0.83 GAA (0.50) CYP3A4SMN1; SMN2CA1CA2CA12
SCHEMBL28543490 0.83 GAA (0.50) CYP3A4SMN1; SMN2CA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1457511-B1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME MITSUI CHEMICALS INC (JP) 2009-07-15 EP disclosed
EP-1457511-A1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME Mitsui Chemicals, Inc. (JP) 2004-09-15 EP disclosed