Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 7/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13403049 | 1.00 | MAPT (0.37) | MAPTKDM4ENPC1RAB9AUSP2 | |
| SCHEMBL4520046 | 0.86 | GAA (0.40) | MAPTKDM4ENPC1RAB9AUSP2 | |
| SCHEMBL4522131 | 0.86 | RXFP1 (0.41) | MAPTRXFP1TP53ALDH1A1LMNA | |
| SCHEMBL3495642 | 0.80 | PADI4 (0.35) | MAPTKDM4ENPC1RAB9AUSP2 | |
| SCHEMBL13402968 | 0.78 | RAB9A (0.38) | MAPTNPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL3493934 | 0.78 | RAB9A (0.38) | MAPTNPC1RAB9AHPGDALDH1A1 | |
| SCHEMBL3495389 | 0.74 | KDM4E (0.42) | MAPTKDM4ENPC1RAB9AUSP2 | |
| SCHEMBL3495386 | 0.74 | KDM4E (0.42) | MAPTKDM4ENPC1RAB9AUSP2 | |
| SCHEMBL4523899 | 0.74 | RXFP1 (0.38) | MAPTKDM4ENPC1RAB9AUSP2 | |
| SCHEMBL4523900 | 0.74 | RXFP1 (0.38) | MAPTKDM4ENPC1RAB9AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081652-A1 | Cinnamoyl Compound and Use Thereof | SHIRAKI HIROAKI | 2010-04-01 | — | — | US | disclosed |
| EP-1857455-A1 | CINNAMOYL COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2007-11-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081652-A1 | Cinnamoyl Compound and Use Thereof | COL2A1, MMP7, COL14A1 | MAPT 4000/4885KDM4E 2703/4885NPC1 701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.