SCHEMBL3496402

SCHEMBL3496402

O=C(O)C1C2CCC(O2)C1C(=O)Nc1ccccc1

nearest known ligand 0.78

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.78
KMT2A Q03164 4/20 0.78
MEN1 O00255 3/20 0.78
BLM P54132 1/20 0.78
LMNA P02545 5/20 0.76
TDP1 Q9NUW8 1/20 0.76
PPM1B O75688 2/20 0.66
KDM4E B2RXH2 3/20 0.64
GAA P10253 1/20 0.61
POLB P06746 1/20 0.57
HTT P42858 2/20 0.55
HIF1A Q16665 1/20 0.55
FPR1 P21462 1/20 0.55
HSD17B10 Q99714 1/20 0.55
L3MBTL1 Q9Y468 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13311757 0.88 ALDH1A1 (1.00) ALDH1A1KMT2AMEN1BLMLMNA
SCHEMBL3493983 0.88 ALDH1A1 (1.00) ALDH1A1KMT2AMEN1BLMLMNA
SCHEMBL3495475 0.86 ALDH1A1 (0.76) ALDH1A1KMT2AMEN1BLMLMNA
SCHEMBL3500228 0.86 ALDH1A1 (0.76) ALDH1A1KMT2AMEN1BLMLMNA
SCHEMBL3493897 0.86 KMT2A (0.76) ALDH1A1KMT2AMEN1BLMLMNA
SCHEMBL3494920 0.84 PPM1B (0.67) ALDH1A1KMT2AMEN1BLMLMNA
SCHEMBL3500248 0.84 KMT2A (0.65) ALDH1A1KMT2AMEN1BLMLMNA
SCHEMBL3496283 0.84 LMNA (0.71) ALDH1A1KMT2AMEN1BLMLMNA
SCHEMBL13311427 0.84 ALDH1A1 (0.72) ALDH1A1KMT2AMEN1BLMLMNA
SCHEMBL3496110 0.83 GAA (0.71) ALDH1A1KMT2AMEN1BLMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2086534-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS Genetic Technologies Limited (AU) 2009-08-12 EP claimed
WO-2008058342-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS GENETIC TECHNOLOGIES LIMITED (AU) 2008-05-22 WO claimed
US-20100137294-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS GENETIC TECHNOLOGIES LIMITED (AU) 2010-06-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100137294-A1 COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS PPP1R10, TASP1, PPP5C ALDH1A1 3457/4885KMT2A 1199/4885MEN1 4270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.