SCHEMBL3496480

SCHEMBL3496480

COc1ccc(C(c2ccccc2)(c2ccc(OC)cc2)C(O)CO)cc1

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 11/20 0.54
KCNH2 Q12809 1/20 0.46
CA4 P22748 1/20 0.42
LTA4H P09960 2/20 0.42
LMNA P02545 1/20 0.41
HTT P42858 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
KMT2A Q03164 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8403280 0.87 KIF11 (0.48) KIF11KCNH2CA4LTA4HLMNA
SCHEMBL14937220 0.85 KIF11 (0.46) KIF11KCNH2CA4LTA4HLMNA
SCHEMBL9559237 0.84 KIF11 (0.51) KIF11KCNH2CA4LTA4HLMNA
SCHEMBL6129866 0.83 KIF11 (0.50) KIF11KCNH2LTA4HLMNAHTT
SCHEMBL10586379 0.83 KIF11 (0.54) KIF11KCNH2SMN1; SMN2
SCHEMBL4579061 0.82 KIF11 (0.44) KIF11KCNH2LTA4HLMNAHTT
SCHEMBL8734433 0.82 KIF11 (0.44) KIF11KCNH2LTA4HLMNAHTT
SCHEMBL7747362 0.82 KIF11 (0.44) KIF11KCNH2LTA4HLMNAHTT
SCHEMBL8587190 0.81 KDM4E (0.43) KIF11KCNH2LMNASMN1; SMN2KMT2A
SCHEMBL15517407 0.81 KIF11 (0.56) KIF11KCNH2CA4LTA4HLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2111218-B1 DNA CONTROLLED ASSEMBLY OF LIPID MEMBRANES UNIV SYDDANSK (DK) 2014-07-02 EP disclosed
US-20100144848-A1 DNA CONTROLLED ASSEMBLY OF LIPID MEMBRANES SYDDANSK UNIVERSITET (DK) 2010-06-10 US disclosed
EP-2111218-A1 DNA CONTROLLED ASSEMBLY OF LIPID MEMBRANES Syddansk Universitet (DK) 2009-10-28 EP disclosed
WO-2008089771-A1 DNA CONTROLLED ASSEMBLY OF LIPID MEMBRANES SYDDANSK UNIVERSITET (DK) 2008-07-31 WO disclosed
US-6008398-A Non-nucleotide phosphorus ester oligomers GENZYME CORPORATION (US) 1999-12-28 US disclosed
US-5919965-A Non-nucleotide phosphorus ester oligomers GENZYME CORPORATION (US) 1999-07-06 US disclosed
EP-0880532-A4 NON-NUCLEOTIDE PHOSPHOROUS ESTER OLIGOMERS PHARMAGENICS INC (US) 1999-06-09 EP disclosed
EP-0880532-A1 NON-NUCLEOTIDE PHOSPHOROUS ESTER OLIGOMERS PHARMAGENICS, INC. (US) 1998-12-02 EP disclosed
EP-0804443-A4 NON-NUCLEOTIDE PHOSPHORUS ESTER OLIGOMERS PHARMAGENICS INC (US) 1998-04-29 EP disclosed
EP-0804443-A1 NON-NUCLEOTIDE PHOSPHORUS ESTER OLIGOMERS PHARMAGENICS, INC. (US) 1997-11-05 EP disclosed
WO-1997028168-A1 NON-NUCLEOTIDE PHOSPHOROUS ESTER OLIGOMERS PHARMAGENICS, INC. (US) 1997-08-07 WO disclosed
WO-1996022297-A9 NON-NUCLEOTIDE PHOSPHORUS ESTER OLIGOMERS 1996-10-03 WO disclosed
WO-1996022297-A1 NON-NUCLEOTIDE PHOSPHORUS ESTER OLIGOMERS PHARMAGENICS, INC. (US) 1996-07-25 WO disclosed