Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 9/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8403351 | 1.00 | KDM4E (0.43) | KDM4EGAASMN1; SMN2TDP1HTR1A | |
| SCHEMBL3496480 | 0.81 | KIF11 (0.54) | SMN1; SMN2KIF11KCNH2LMNAKMT2A | |
| SCHEMBL14937220 | 0.80 | KIF11 (0.46) | SMN1; SMN2KIF11KCNH2LMNAKMT2A | |
| SCHEMBL8403280 | 0.79 | KIF11 (0.48) | SMN1; SMN2KIF11KCNH2LMNAKMT2A | |
| SCHEMBL9559237 | 0.79 | KIF11 (0.51) | SMN1; SMN2KIF11KCNH2LMNAKMT2A | |
| SCHEMBL10586379 | 0.78 | KIF11 (0.54) | SMN1; SMN2KIF11KCNH2 | |
| SCHEMBL29451221 | 0.78 | SMN1; SMN2 (0.43) | GAASMN1; SMN2KIF11LMNAKMT2A | |
| SCHEMBL5065127 | 0.75 | KIF11 (0.45) | SMN1; SMN2KIF11KCNH2LMNAKMT2A | |
| SCHEMBL8080069 | 0.75 | KIF11 (0.51) | KIF11KCNH2KMT2A | |
| SCHEMBL8539261 | 0.75 | AOC3 (0.50) | KDM4EGAASMN1; SMN2TDP1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0804443-A4 | NON-NUCLEOTIDE PHOSPHORUS ESTER OLIGOMERS | PHARMAGENICS INC (US) | 1998-04-29 | — | — | EP | disclosed |
| EP-0804443-A1 | NON-NUCLEOTIDE PHOSPHORUS ESTER OLIGOMERS | PHARMAGENICS, INC. (US) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996022297-A1 | NON-NUCLEOTIDE PHOSPHORUS ESTER OLIGOMERS | PHARMAGENICS, INC. (US) | 1996-07-25 | — | — | WO | disclosed |