Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3496869 | 0.82 | POLA1 (0.70) | POLA1 | |
| SCHEMBL3498548 | 0.82 | POLA1 (0.75) | POLA1 | |
| SCHEMBL28004910 | 0.79 | POLA1 (0.67) | POLA1 | |
| SCHEMBL28004895 | 0.79 | POLA1 (0.74) | POLA1 | |
| SCHEMBL1286951 | 0.79 | — | — | |
| SCHEMBL18231630 | 0.77 | POLA1 (0.64) | POLA1 | |
| SCHEMBL29459145 | 0.77 | — | — | |
| SCHEMBL20592340 | 0.77 | — | — | |
| SCHEMBL6272738 | 0.76 | XDH (1.00) | POLA1XDH | |
| SCHEMBL10798703 | 0.75 | POLA1 (1.00) | POLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100143332-A1 | COMBINATION THERAPY FOR PROLIFERATIVE DISORDERS | SCHERING CORPORATION | 2010-06-10 | — | — | US | claimed |
| EP-2086644-A2 | COMBINATION OF AN INHIBITOR OF DNA POLYMERASE-ALPHA AND AN INHIBITOR OF A CHECKPOINT KINASE FOR PROLIFERATIVE DISORDERS | SCHERING CORPORATION (US) | 2009-08-12 | — | — | EP | claimed |
| WO-2008063558-A2 | COMBINATION OF AN INHIBITOR OF DNA POLYMERASE-ALPHA AND AN INHIBITOR OF A CHECKPOINT KINASE FOR PROLIFERATIVE DISORDERS | SCHERING CORPORATION (US) | 2008-05-29 | — | — | WO | claimed |
| US-20100143332-A1 | COMBINATION THERAPY FOR PROLIFERATIVE DISORDERS | SCHERING CORPORATION | 2010-06-10 | — | — | US | disclosed |
| EP-2086644-A2 | COMBINATION OF AN INHIBITOR OF DNA POLYMERASE-ALPHA AND AN INHIBITOR OF A CHECKPOINT KINASE FOR PROLIFERATIVE DISORDERS | SCHERING CORPORATION (US) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008063558-A2 | COMBINATION OF AN INHIBITOR OF DNA POLYMERASE-ALPHA AND AN INHIBITOR OF A CHECKPOINT KINASE FOR PROLIFERATIVE DISORDERS | SCHERING CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |