Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL349740 | 0.82 | ADORA2A (0.31) | ADORA2A | |
| SCHEMBL350387 | 0.78 | ADORA2A (0.34) | ADORA2A | |
| SCHEMBL2676370 | 0.72 | CTNNB1 (0.31) | NOTUM | |
| SCHEMBL351866 | 0.71 | — | — | |
| SCHEMBL6264335 | 0.69 | AHR (0.45) | — | |
| SCHEMBL8778320 | 0.69 | ALOX5 (0.41) | NOTUM | |
| SCHEMBL12879229 | 0.67 | ADORA2A (0.37) | ADORA2A | |
| SCHEMBL16042690 | 0.67 | ADORA2A (0.32) | ADORA2A | |
| SCHEMBL6904035 | 0.65 | ABCG2 (0.36) | — | |
| SCHEMBL351151 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120015981-A1 | Active compound combinations | BAYER CORPSCIENCE AG (DE) | 2012-01-19 | — | — | US | disclosed |
| EP-2391213-A1 | ACTIVE COMPOUND COMBINATIONS | Bayer CropScience AG (DE) | 2011-12-07 | — | — | EP | disclosed |
| US-20110294855-A1 | Active Compound Combinations | BAYER CROPSCIENCE AG (DE) | 2011-12-01 | — | — | US | disclosed |
| WO-2010086120-A1 | ACTIVE COMPOUND COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2010-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294855-A1 | Active Compound Combinations | PFAS, AFF1, AFF2 | NOTUM 45/4885ADORA2A 2450/4885 |
| US-20120015981-A1 | Active compound combinations | PFAS, CBR3, AADAC | NOTUM 23/4885ADORA2A 2529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.