Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL350387 | 0.80 | ADORA2A (0.34) | ADORA2A | |
| SCHEMBL2676370 | 0.73 | CTNNB1 (0.31) | — | |
| SCHEMBL17600989 | 0.67 | FFAR4 (0.38) | — | |
| Hydrochloric Acid SCHEMBL10371157 | 0.67 | ADORA2A (0.39) | ADORA2A | |
| SCHEMBL910176 | 0.64 | ITGB2 (0.37) | — | |
| SCHEMBL3288378 | 0.63 | MPO (0.44) | ADORA2A | |
| SCHEMBL978248 | 0.62 | MPO (0.33) | ADORA2A | |
| SCHEMBL423294 | 0.62 | ADORA2A (0.35) | ADORA2A | |
| SCHEMBL3151886 | 0.62 | FFAR4 (0.34) | ADORA2A | |
| SCHEMBL334653 | 0.62 | MPO (0.39) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120015981-A1 | Active compound combinations | BAYER CORPSCIENCE AG (DE) | 2012-01-19 | — | — | US | disclosed |
| EP-2391214-A1 | ACTIVE COMPOUND COMBINATIONS | Bayer CropScience AG (DE) | 2011-12-07 | — | — | EP | disclosed |
| US-20110294855-A1 | Active Compound Combinations | BAYER CROPSCIENCE AG (DE) | 2011-12-01 | — | — | US | disclosed |
| WO-2010086109-A1 | ACTIVE COMPOUND COMBINATIONS | BAYER CROPSCIENCE AG (DE) | 2010-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294855-A1 | Active Compound Combinations | PFAS, AFF1, AFF2 | ADORA2A 2450/4885 |
| US-20120015981-A1 | Active compound combinations | PFAS, CBR3, AADAC | ADORA2A 2529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.