Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 8/20 | 0.70 |
| ▸ | TNKS2 | Q9H2K2 | 8/20 | 0.70 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.70 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.70 |
| ▸ | PARP1 | P09874 | 4/20 | 0.66 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.58 |
| ▸ | TUBB | P07437 | 1/20 | 0.58 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.58 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.58 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.58 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.58 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.58 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.58 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.58 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.58 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.58 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.58 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.58 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.58 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30112662 | 1.00 | TNKS (0.70) | TNKSTNKS2CYP1A1CYP1B1PARP1 | |
| SCHEMBL2155329 | 0.86 | HPGD (0.69) | TNKSTNKS2CYP1A1CYP1B1PARP1 | |
| SCHEMBL2617083 | 0.85 | TNKS (0.77) | TNKSTNKS2CYP1A1CYP1B1PARP1 | |
| SCHEMBL29784068 | 0.83 | TNKS (1.00) | TNKSTNKS2CYP1A1CYP1B1PARP1 | |
| SCHEMBL5795292 | 0.83 | TNKS (1.00) | TNKSTNKS2CYP1A1CYP1B1PARP1 | |
| SCHEMBL17904243 | 0.82 | TNKS (0.71) | TNKSTNKS2CYP1A1CYP1B1PARP1 | |
| SCHEMBL10430064 | 0.82 | TNKS (0.62) | TNKSTNKS2CYP1A1CYP1B1PARP1 | |
| SCHEMBL4712542 | 0.81 | PTGES (0.53) | TNKSTNKS2CYP1A1CYP1B1TUBB4A | |
| SCHEMBL11826929 | 0.81 | TNKS (0.70) | TNKSTNKS2CYP1A1CYP1B1PARP1 | |
| SCHEMBL11311043 | 0.81 | TNKS (0.70) | TNKSTNKS2CYP1A1CYP1B1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117964560-A | Method for constructing quinazolinone derivative through oxidization | 淮阴工学院 | 2024-05-03 | — | — | CN | disclosed |
| CN-111777564-B | Method for synthesizing quinazolinone compound by photocatalytic alcohol oxidation in aqueous phase | 许昌学院 | 2023-07-14 | — | — | CN | disclosed |
| CN-111875549-B | Method for synthesizing quinazolinone compound in aqueous phase through photocatalysis | 许昌学院 | 2023-04-28 | — | — | CN | disclosed |
| CN-112645887-B | Preparation method of quinazolinone derivative | 淮阴工学院（CN） | 2023-01-13 | — | — | CN | disclosed |
| CN-112645887-A | Preparation method of quinazolinone derivative | 淮阴工学院 | 2021-04-13 | — | — | CN | disclosed |
| CN-111875549-A | Method for synthesizing quinazolinone compound in aqueous phase through photocatalysis | 许昌学院 | 2020-11-03 | — | — | CN | disclosed |
| CN-111777564-A | Method for synthesizing quinazolinone compound through photocatalytic alcohol oxidation in aqueous phase | 许昌学院 | 2020-10-16 | — | — | CN | disclosed |
| CN-106478525-A | A kind of method of synthesis quinazolone | 南京理工大学 | 2017-03-08 | — | — | CN | disclosed |
| US-20100160314-A1 | Small Molecule Inhibitors of Toll-Like Receptor 9 | LIPFORD GRAYSON B | 2010-06-24 | — | — | US | disclosed |
| US-20100160314-A1 | Small Molecule Inhibitors of Toll-Like Receptor 9 | LIPFORD GRAYSON B | 2010-06-24 | — | — | US | disclosed |
| US-20100160314-A1 | Small Molecule Inhibitors of Toll-Like Receptor 9 | LIPFORD GRAYSON B | 2010-06-24 | — | — | US | disclosed |
| EP-2081924-A2 | SMALL MOLECULE INHIBITORS OF TOLL-LIKE RECEPTOR 9 | Coley Pharmaceutical Group, Inc. (US) | 2009-07-29 | — | — | EP | disclosed |
| WO-2008030455-A2 | SMALL MOLECULE INHIBITORS OF TOLL-LIKE RECEPTOR 9 | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2008-03-13 | — | — | WO | disclosed |
| WO-2008030455-A2 | SMALL MOLECULE INHIBITORS OF TOLL-LIKE RECEPTOR 9 | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2008-03-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160314-A1 | Small Molecule Inhibitors of Toll-Like Receptor 9 | TLR9, TLR3, TLR1 | TNKS 495/4885TNKS2 859/4885CYP1A1 4833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.