Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TFPI2 | P48307 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13311403 | 1.00 | ALDH1A1 (0.48) | ALDH1A1LMNAMAPK1TDP1TSHR | |
| SCHEMBL13311589 | 0.85 | LMNA (0.46) | ALDH1A1LMNAMAPK1TSHRTFPI2 | |
| SCHEMBL13311369 | 0.75 | LMNA (0.57) | ALDH1A1LMNAMAPK1TSHRTFPI2 | |
| SCHEMBL17384921 | 0.75 | LMNA (0.57) | ALDH1A1LMNAMAPK1TSHRTFPI2 | |
| SCHEMBL3494928 | 0.75 | LMNA (0.57) | ALDH1A1LMNAMAPK1TSHRTFPI2 | |
| SCHEMBL19986242 | 0.74 | ALDH1A1 (0.49) | ALDH1A1TDP1TSHRKDM4EL3MBTL1 | |
| SCHEMBL19971687 | 0.74 | ALDH1A1 (0.46) | ALDH1A1LMNATDP1TSHRL3MBTL1 | |
| SCHEMBL19971685 | 0.74 | ALDH1A1 (0.46) | ALDH1A1LMNATDP1TSHRL3MBTL1 | |
| SCHEMBL19971686 | 0.74 | ALDH1A1 (0.46) | ALDH1A1LMNATDP1TSHRL3MBTL1 | |
| SCHEMBL30522606 | 0.74 | TDP1 (0.75) | ALDH1A1LMNATDP1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100137294-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS | GENETIC TECHNOLOGIES LIMITED (AU) | 2010-06-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137294-A1 | COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING INVERTEBRATE PESTS | PPP1R10, TASP1, PPP5C | ALDH1A1 3457/4885LMNA 4332/4885MAPK1 812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.