Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL11566968 | 0.90 | LMNA (0.47) | — | |
| SCHEMBL7802076 | 0.89 | LMNA (0.60) | — | |
| SCHEMBL42798 | 0.89 | — | — | |
| Ammonia Solution, Strong SCHEMBL8081452 | 0.86 | — | — | |
| SCHEMBL27476183 | 0.86 | — | — | |
| Propylene Glycol SCHEMBL16933782 | 0.85 | TDP1 (0.56) | — | |
| Glycerin SCHEMBL5764240 | 0.83 | LMNA (0.47) | — | |
| Di(Hydroxyethyl)Ether SCHEMBL4830573 | 0.81 | ALDH1A1 (0.55) | — | |
| Chloroform SCHEMBL7162031 | 0.80 | LMNA (0.50) | — | |
| Ether SCHEMBL11433738 | 0.80 | LMNA (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-27 | — | — | US | disclosed |
| EP-1849465-A1 | AGENT FOR CONTROLLING FUNCTION OF GPR34 RECEPTOR | Takeda Pharmaceutical Company Limited (JP) | 2007-10-31 | — | — | EP | disclosed |