SCHEMBL349782

SCHEMBL349782

O=C1OC(=O)C2CC1C1C(=O)OC(=O)C21

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.46
GMNN O75496 1/20 0.46
PPM1B O75688 1/20 0.46
LMNA P02545 1/20 0.46
PPP1CC P36873 1/20 0.46
TFPI2 P48307 1/20 0.46
RAB9A P51151 1/20 0.46
PPP5C P53041 1/20 0.46
PPP1CA P62136 1/20 0.46
PMP22 Q01453 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
TP53 P04637 1/20 0.46
CYP2D6 P10635 1/20 0.46
NFKB1 P19838 1/20 0.46
THPO P40225 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18055917 1.00 KDM4E (0.46) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL2695589 1.00 KDM4E (0.46) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL15643871 1.00 KDM4E (0.46) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL2700698 1.00 KDM4E (0.46) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL2698859 1.00 KDM4E (0.46) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL2698566 1.00 KDM4E (0.46) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL2697373 1.00 KDM4E (0.46) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL17974212 1.00 KDM4E (0.46) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL13084714 1.00 KDM4E (0.46) KDM4EGMNNPPM1BLMNAPPP1CC
SCHEMBL23393579 0.97 KDM4E (0.44) KDM4EGMNNPPM1BLMNAPPP1CC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 99 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11561440-B2 Photoalignment composition for the stabilization of the pre-tilt angle in liquid crystal layers Rolic Technologies AG (CH) 2023-01-24 US claimed
EP-4634327-A1 COMPOSITION FOR FORMING A LIQUID CRYSTAL ALIGNMENT FILM Rolic Technologies AG (CH) 2025-10-22 EP disclosed
CN-119614213-A Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 日产化学株式会社 2025-03-14 CN disclosed
CN-114609830-B Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element 日产化学株式会社 2025-02-21 CN disclosed
WO-2024125945-A1 COMPOSITION FOR FORMING A LIQUID CRYSTAL ALIGNMENT FILM Rolic Technologies AG (CH) 2024-06-20 WO disclosed
CN-111936922-B Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 日产化学株式会社 2023-05-26 CN disclosed
US-11634544-B2 Photoaligning materials Rolic Technologies AG (CH) 2023-04-25 US disclosed
US-11561440-B2 Photoalignment composition for the stabilization of the pre-tilt angle in liquid crystal layers Rolic Technologies AG (CH) 2023-01-24 US disclosed
CN-110462501-B Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element 日产化学株式会社 2022-10-28 CN disclosed
CN-109971494-B Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element JSR株式会社 2022-08-30 CN disclosed
US-20110065859-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2011-03-17 US disclosed
US-20110043739-A1 LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE JSR CORPORATION (JP) 2011-02-24 US disclosed
US-20110007254-A1 COMPOSITION FOR FORMING A LIQUID CRYSTAL ALIGNMENT FILM, AND LIQUID CRYSTAL DISPLAY DEVICE SHARP KABUSHIKI KAISHA (JP) 2011-01-13 US disclosed
EP-2259133-A1 COMPOSITION FOR FORMING LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL DISPLAY DEVICE Sharp Kabushiki Kaisha (JP) 2010-12-08 EP disclosed
EP-2256541-A1 A LIQUID CRYSTAL ORIENTATING AGENT, A LIQUID CRYSTAL ORIENTATING FILM AND A LIQUID CRYSTAL DISPLAY ELEMENT JSR Corporation (JP) 2010-12-01 EP disclosed
US-20100048849-A1 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP ROLIC AG (CH) 2010-02-25 US disclosed
EP-2152660-A2 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP Rolic AG (CH) 2010-02-17 EP disclosed
EP-2144951-A1 THERMALLY STABLE ALIGNMENT MATERIALS Rolic AG (CH) 2010-01-20 EP disclosed
WO-2008145225-A2 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP ROLIC AG (CH) 2008-12-04 WO disclosed
WO-2008135131-A1 THERMALLY STABLE ALIGNMENT MATERIALS ROLIC AG (CH) 2008-11-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100048849-A1 PHOTOCROSSLINKABLE MATERIALS COMPRISING ALICYCLIC GROUP DDC, ALAD, DYNC1LI1 KDM4E 1369/4885GMNN 297/4885PPM1B 3628/4885
US-20110065859-A1 THERMALLY STABLE ALIGNMENT MATERIALS PARG, PARN, PUF60 KDM4E 2018/4885GMNN 237/4885PPM1B 2963/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.