Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | DRD4 | P21917 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Toluene SCHEMBL4953353 | 0.93 | LTA4H (0.50) | TSHRALDH1A1LTA4HLMNAALOX12 | |
| Toluene SCHEMBL27590448 | 0.92 | TSHR (0.45) | TSHRALDH1A1LTA4HLMNAALOX12 | |
| Toluene SCHEMBL11062278 | 0.91 | LTA4H (0.48) | TSHRALDH1A1LTA4HLMNAALOX12 | |
| Butoxyethanol SCHEMBL5892032 | 0.90 | TSHR (0.63) | TSHRALDH1A1LTA4HLMNAALOX12 | |
| Toluene SCHEMBL9105788 | 0.90 | TSHR (0.52) | TSHRALDH1A1LTA4HLMNAALOX12 | |
| Butoxyethanol SCHEMBL9105780 | 0.89 | TSHR (0.61) | TSHRALDH1A1LTA4HLMNAALOX12 | |
| P-Xylene SCHEMBL27374298 | 0.88 | TSHR (0.50) | TSHRALDH1A1LTA4HLMNAACHE | |
| P-Xylene SCHEMBL28282785 | 0.86 | TSHR (0.48) | TSHRALDH1A1LMNAACHEHPGD | |
| Toluene SCHEMBL27526151 | 0.85 | MEN1 (0.60) | TSHRALDH1A1LTA4HLMNAALOX12 | |
| Toluene SCHEMBL8093134 | 0.84 | LTA4H (0.48) | TSHRLTA4HLMNAALOX12ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103172480-B | Method for preparing iodo aromatic hydrocarbon | UNIV HENAN SCIENCE & TECH | 2015-01-21 | — | — | CN | claimed |
| CN-101501078-A | Process for preparing a catalyst component for the polymerization of olefins | BASELL POLIOLEFINE SRL (IT) | 2009-08-05 | — | — | CN | claimed |
| US-7425629-B2 | Stereoselective synthesis of certain trifluoromethyl-substituted alcohols | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2008-09-16 | — | — | US | claimed |
| EP-1934218-A1 | STEREOSELECTIVE SYNTHESIS OF CERTAIN TRIFLUOROMETHYL-SUBSTITUTED ALCOHOLS | Boehringer Ingelheim International GmbH (DE) | 2008-06-25 | — | — | EP | claimed |
| US-20070100142-A1 | Reacting 1-amino-2-hydroxy-indene with a first protecting group containing a leaving group, followed by acetylation to prepare a protected intermediate, reacting with trifluoromethyl substituted ketone, then with metal oxide, hydrolysis, esterification, reaction with amino-picoline | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2007-05-03 | — | — | US | claimed |
| WO-2007040959-A1 | STEREOSELECTIVE SYNTHESIS OF CERTAIN TRIFLUOROMETHYL-SUBSTITUTED ALCOHOLS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-04-12 | — | — | WO | claimed |
| US-4902826-A | REACTING LITHIUM 2-CHLOROBENZOATE WITH LITHIUM THIOPHENOXIDE OR DERIVATIVE | BAYER AKTIENGESELLSCHAFT (DE) | 1990-02-20 | — | — | US | claimed |
| CN-118005827-A | Photopolymerization initiator | 科巨希化学股份有限公司 | 2024-05-10 | — | — | CN | disclosed |
| CN-114929757-B | Photopolymerization initiator | 科巨希化学股份有限公司 | 2024-02-20 | — | — | CN | disclosed |
| CN-109416957-A | Refractive index matching layers for optical application | 霍尼韦尔国际公司 | 2019-03-01 | — | — | CN | disclosed |
| CN-106414475-B | The method for producing the derovatives of 21 methoxyl group, 11 β phenyl, 19 norpregna, 4,9 diene 3,20 | 吉瑞工厂 | 2018-04-10 | — | — | CN | disclosed |
| US-20180022642-A1 | INDEX MATCHING LAYER IN OPTICAL APPLICATIONS | HONEYWELL INTERNATIONAL INC. | 2018-01-25 | — | — | US | disclosed |
| US-9871225-B2 | Organic electroluminescence element | Konica Minolta, Inc. (JP) | 2018-01-16 | — | — | US | disclosed |
| US-20050239264-A1 | Materials suitable for shallow trench isolation | HONEYWELL INTERNATIONAL INC. | 2005-10-27 | — | — | US | disclosed |
| CN-1052490-C | Method for increasing alpha to beta ratio in aspartame coupling reaction | NUTRASWEET CO (US) | 2000-05-17 | — | — | CN | disclosed |
| US-5071898-A | Chlorinated vinyl and polyolefin resin; heat resistance | CIBA-GEIGY CORPORATION (US) | 1991-12-10 | — | — | US | disclosed |
| CN-1055539-A | The method of α and beta ratio in raising L-aspartyl-L-phenyl methyl lactamine coupled reaction | NUTRASWEET CO (US) | 1991-10-23 | — | — | CN | disclosed |
| EP-0416272-A1 | Formed organosiloxanaminpolycondensates, process for their preparation and their use | Degussa Aktiengesellschaft (DE) | 1991-03-13 | — | — | EP | disclosed |
| US-4315835-A | MAGNESIUM GRIGNARD REAGENT AND TITANIUM COMPONENT | MONTEDISON S.P.A. (IT) | 1982-02-16 | — | — | US | disclosed |
| US-4220554-A | MAGNESIUM-TITANIUM CATALYST | MONTEDISON S.P.A. (IT) | 1980-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070100142-A1 | Reacting 1-amino-2-hydroxy-indene with a first protecting group containing a leaving group, followed by acetylation to prepare a protected intermediate, reacting with trifluoromethyl substituted ketone, then with metal oxide, hydrolysis, esterification, reaction with amino-picoline | ALDH7A1, AADAT, ALDH18A1 | TSHR 2349/4885ALDH1A1 73/4885LTA4H 1184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.