SCHEMBL3497994

SCHEMBL3497994

O=C1COCCOCCOCC(=O)O1

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.46
TSHR P16473 2/20 0.42
TTR P02766 1/20 0.38
ALDH1A1 P00352 1/20 0.35
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL88159 0.83
SCHEMBL6121060 0.79 GAA (0.44) GAATSHRTTRALDH1A1LMNA
SCHEMBL1933467 0.79 GAA (0.44) GAATSHRTTRALDH1A1LMNA
Dioxane SCHEMBL6669275 0.79 GAA (0.44) GAATSHRTTRALDH1A1LMNA
SCHEMBL7200305 0.79 GAA (0.44) GAATSHRTTRALDH1A1LMNA
SCHEMBL29008 0.75
SCHEMBL4394616 0.75
SCHEMBL278292 0.75 LMNA (0.42) GAATSHRALDH1A1LMNATP53
SCHEMBL1933520 0.75 LMNA (0.42) GAATSHRALDH1A1LMNATP53
Methane SCHEMBL29072799 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2111237-B1 FIBRIN-BINDING PEPTIDES AND CONJUGATES THEREOF BRACCO IMAGING SPA (IT) 2015-03-18 EP disclosed
US-8278274-B2 Fibrin-binding peptides and conjugates thereof BRACCO IMAGING SPA (IT) 2012-10-02 US disclosed
US-20100158814-A1 Fibrin-Binding Peptides and Conjugates Thereof BRACCO IMAGING S.P.A. (IT) 2010-06-24 US disclosed
EP-2111237-A2 FIBRIN-BINDING PEPTIDES AND CONJUGATES THEREOF BRACCO IMAGING S.p.A. (IT) 2009-10-28 EP disclosed
WO-2008073458-A2 FIBRIN-BINDING PEPTIDES AND CONJUGATES THEREOF BRACCO IMAGING S.P.A. (IT) 2008-06-19 WO disclosed
EP-0534772-A2 Oxidising compositions WARWICK INTERNATIONAL GROUP LIMITED(Company No. 2754514) (GB) 1993-03-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100158814-A1 Fibrin-Binding Peptides and Conjugates Thereof FGB, F13B, F13A1 GAA 2907/4885TSHR 1126/4885TTR 198/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.