Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3499959 | 1.00 | S100B (0.43) | S100BAPPCA2CA12CA9 | |
| SCHEMBL7822309 | 0.87 | S100B (0.59) | S100BAPPCA2CA12CA9 | |
| SCHEMBL7822307 | 0.87 | S100B (0.59) | S100BAPPCA2CA12CA9 | |
| SCHEMBL2746630 | 0.86 | CA2 (0.44) | S100BCA2CA12CA9PTGS2 | |
| SCHEMBL2746628 | 0.86 | CA2 (0.44) | S100BCA2CA12CA9PTGS2 | |
| SCHEMBL1118830 | 0.81 | PREP (0.50) | APPCA2CA12CA9PREP | |
| SCHEMBL4024641 | 0.77 | KMT2A (0.49) | CA12CA9ALDH1A1KDM4EMEN1 | |
| SCHEMBL20871788 | 0.77 | S100B (0.70) | S100BAPPCA2CA12CA9 | |
| SCHEMBL4024645 | 0.77 | KMT2A (0.49) | CA12CA9ALDH1A1KDM4EMEN1 | |
| SCHEMBL7189378 | 0.72 | CA12 (0.46) | CA12CA9PTGS2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100125059-A1 | 1-BIARYLAZETIDINONE DERIVATIVE | TEIJIN PHARMA LIMITED (JP) | 2010-05-20 | — | — | US | disclosed |
| EP-2133347-A1 | 1-BIARYLAZETIDINONE DERIVATIVES | Teijin Pharma Limited (JP) | 2009-12-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100125059-A1 | 1-BIARYLAZETIDINONE DERIVATIVE | PCSK9, CYP46A1, HMGCR | S100B 4793/4885APP 1895/4885CA2 2690/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.