SCHEMBL3498540

SCHEMBL3498540

CCCCCCOCCC(COCCCCCC)OC(=O)CCCCC(=O)O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.57
LMNA P02545 5/20 0.54
ALDH1A1 P00352 1/20 0.54
MAPK1 P28482 5/20 0.53
MAPT P10636 4/20 0.53
PLA2G2C Q5R387 1/20 0.51
GMNN O75496 3/20 0.50
NPSR1 Q6W5P4 3/20 0.50
CYP1A2 P05177 3/20 0.50
MEN1 O00255 2/20 0.50
HSP90AA1 P07900 2/20 0.50
BLM P54132 2/20 0.50
KMT2A Q03164 2/20 0.50
NR1H4 Q96RI1 2/20 0.50
PRKCA P17252 1/20 0.50
PRKCE Q02156 1/20 0.50
PRKCQ Q04759 1/20 0.50
PRKCD Q05655 1/20 0.50
TP53 P04637 1/20 0.50
CYP2C9 P11712 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14952939 0.87 PRKCA (0.67) RECQLLMNAALDH1A1MAPK1MAPT
SCHEMBL8603195 0.85 LMNA (0.72) RECQLLMNAALDH1A1MAPK1MAPT
SCHEMBL25867057 0.85 LMNA (0.72) RECQLLMNAALDH1A1MAPK1MAPT
SCHEMBL24372449 0.85 LMNA (0.72) RECQLLMNAALDH1A1MAPK1MAPT
SCHEMBL24811917 0.84 ALDH1A1 (0.72) LMNAALDH1A1MAPK1MAPTPRKCA
SCHEMBL7532789 0.83 MAPK1 (0.59) LMNAALDH1A1MAPK1MAPTGMNN
SCHEMBL18632861 0.82 LMNA (0.72) LMNAALDH1A1MAPK1MAPTPRKCA
SCHEMBL18257502 0.82 LMNA (0.72) LMNAALDH1A1MAPK1MAPTPRKCA
SCHEMBL10893167 0.81 MAPT (0.75) LMNAALDH1A1MAPK1MAPTPRKCA
SCHEMBL9070261 0.81 MAPT (0.75) LMNAALDH1A1MAPK1MAPTPRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160369237-A1 METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY ADVANCED CELL TECH INC (US) 2016-12-22 US disclosed
US-20100184033-A1 METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY Lineage Cell Therapeutics, Inc. 2010-07-22 US disclosed
US-20080226601-A1 Herpes Virus-Based Compositions and Methods of Use in the Prenatal and Perinatal Periods UNIVERSITY OF ROCHESTER (US) 2008-09-18 US disclosed
EP-1903873-A2 HERPES VIRUS-BASED COMPOSITIONS AND METHODS OF USE IN THE PRENATAL AND PERINATAL PERIODS THE UNIVERSITY OF ROCHESTER (US) 2008-04-02 EP disclosed
US-20080070303-A1 Using myocardial and/or muscle progenitor cells as modeling tool in tissue engineering; regenerative medicine and organ replacement ADVANCED CELL TECHNOLOGY 2008-03-20 US disclosed
WO-2006135602-A2 HERPES VIRUS-BASED COMPOSITIONS AND METHODS OF USE IN THE PRENATAL AND PERINATAL PERIODS UNIVERSITY OF ROCHESTER (US) 2006-12-21 WO disclosed