Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR34 | Q9UPC5 | 8/20 | 0.51 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | CDC25B | P30305 | 1/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.45 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3498699 | 1.00 | GPR34 (0.51) | GPR34GPR132PPARGPTPN1PTPN2 | |
| SCHEMBL3502020 | 0.93 | RAB9A (0.48) | GPR34PPARGFFAR1 | |
| SCHEMBL3502021 | 0.93 | RAB9A (0.48) | GPR34PPARGFFAR1 | |
| SCHEMBL3501013 | 0.90 | GPR34 (0.51) | GPR34GPR132PPARGPTPN1FFAR1 | |
| SCHEMBL3501018 | 0.90 | GPR34 (0.51) | GPR34GPR132PPARGPTPN1FFAR1 | |
| SCHEMBL3499151 | 0.89 | MME (0.47) | GPR34GPR132PPARGPTPN1ITGA4 | |
| SCHEMBL3500730 | 0.86 | GPR34 (0.50) | GPR34GPR132PPARGPTPN1PTPN2 | |
| SCHEMBL3500727 | 0.86 | GPR34 (0.50) | GPR34GPR132PPARGPTPN1PTPN2 | |
| SCHEMBL3498179 | 0.86 | GPR34 (0.65) | GPR34GPR132PPARGPTPN1PTPN2 | |
| SCHEMBL3498166 | 0.86 | GPR34 (0.53) | GPR34GPR132PPARGMMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-27 | — | — | US | disclosed |
| EP-1849465-A1 | AGENT FOR CONTROLLING FUNCTION OF GPR34 RECEPTOR | Takeda Pharmaceutical Company Limited (JP) | 2007-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | GPR34, GPR4, GPR6 | GPR34 1/4885GPR132 13/4885PPARG 189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.