Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.53 |
| ▸ | F9 | P00740 | 8/20 | 0.51 |
| ▸ | F10 | P00742 | 5/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.49 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | BAD | Q92934 | 1/20 | 0.46 |
| ▸ | CLK1 | P49759 | 3/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.42 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.42 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22777736 | 0.87 | F9 (0.67) | BCL2L1F9F10GPR35CLK1 | |
| SCHEMBL121331 | 0.87 | F9 (0.67) | BCL2L1F9F10GPR35CLK1 | |
| SCHEMBL2897390 | 0.86 | BCL2L1 (0.59) | BCL2L1GPR35CLK1DYRK1ADYRK1B | |
| SCHEMBL29742282 | 0.86 | BCL2L1 (0.59) | BCL2L1GPR35CLK1DYRK1ADYRK1B | |
| SCHEMBL3498018 | 0.84 | BCL2L1 (0.53) | BCL2L1F9F10GPR35CLK1 | |
| SCHEMBL3497047 | 0.84 | BCL2L1 (0.53) | BCL2L1F9F10GPR35CLK1 | |
| SCHEMBL3497776 | 0.83 | P2RY14 (0.50) | BCL2L1F9GPR35PTPN2 | |
| SCHEMBL15697500 | 0.83 | BCL2L1 (0.51) | BCL2L1F9GPR35MAPK14DYRK1A | |
| SCHEMBL3496932 | 0.80 | CLK1 (0.55) | BCL2L1F9F10CLK1DYRK1A | |
| SCHEMBL3500337 | 0.80 | BCL2L1 (0.49) | BCL2L1F9F10GPR35CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-27 | — | — | US | disclosed |
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-27 | — | — | US | disclosed |
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-27 | — | — | US | disclosed |
| EP-1849465-A1 | AGENT FOR CONTROLLING FUNCTION OF GPR34 RECEPTOR | Takeda Pharmaceutical Company Limited (JP) | 2007-10-31 | — | — | EP | disclosed |
| EP-1849465-A1 | AGENT FOR CONTROLLING FUNCTION OF GPR34 RECEPTOR | Takeda Pharmaceutical Company Limited (JP) | 2007-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | GPR34, GPR4, GPR6 | BCL2L1 2669/4885F9 4781/4885F10 4429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.