Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL436255 | 0.77 | — | — | |
| SCHEMBL20849730 | 0.74 | — | — | |
| SCHEMBL3500103 | 0.71 | — | — | |
| SCHEMBL19503747 | 0.69 | — | — | |
| SCHEMBL24760 | 0.67 | — | — | |
| SCHEMBL6523333 | 0.67 | ALDH1A1 (0.50) | TSHRALDH1A1NFKB1THPOHSD17B10 | |
| SCHEMBL14328624 | 0.67 | TAS2R38 (0.47) | ALDH1A1HSD17B10CA1 | |
| SCHEMBL5317417 | 0.65 | TSHR (0.41) | TSHRALDH1A1NFKB1THPOHSD17B10 | |
| Acetic Acid SCHEMBL27795666 | 0.65 | FFAR3 (0.54) | TSHRALDH1A1NFKB1THPOHSD17B10 | |
| SCHEMBL19789240 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180215687-A1 | SYNTHESIS OF ARYL COMPOUNDS | BOULOS & COOPER PHARMACEUTICALS PTY LTD (AU) | 2018-08-02 | — | — | US | disclosed |
| US-9738591-B2 | Antimicrobial compounds | Boulos, Ramiz (AU) | 2017-08-22 | — | — | US | disclosed |
| US-20170029359-A1 | ANTIMICROBIAL COMPOUNDS | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2017-02-02 | — | — | US | disclosed |
| US-20160220694-A1 | Vitamin-Receptor Binding Drug Delivery Conjugates | ENDOCYTE INC (US) | 2016-08-04 | — | — | US | disclosed |
| US-20150189873-A1 | ANTIMICROBIAL COMPOUNDS | BOULOS & COOPER PHARMACEUTICALS PTY LTD (AU) | 2015-07-09 | — | — | US | disclosed |
| US-9023892-B2 | Antimicrobial compounds | Boulos, Ramiz (AU) | 2015-05-05 | — | — | US | disclosed |
| US-8765096-B2 | Methods and compositions for treating and diagnosing kidney disease | ENDOCYTE, INC (US) | 2014-07-01 | — | — | US | disclosed |
| US-8765096-B2 | Methods and compositions for treating and diagnosing kidney disease | ENDOCYTE, INC (US) | 2014-07-01 | — | — | US | disclosed |
| US-20140058063-A1 | VITAMIN RECEPTOR BINDING DRUG DELIVERY CONJUGATES | ENDOCYTE, INC. (US) | 2014-02-27 | — | — | US | disclosed |
| US-20140058063-A1 | VITAMIN RECEPTOR BINDING DRUG DELIVERY CONJUGATES | ENDOCYTE, INC. (US) | 2014-02-27 | — | — | US | disclosed |
| US-20120329871-A1 | ANTIMICROBIAL COMPOUNDS | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2012-12-27 | — | — | US | disclosed |
| US-20120270791-A1 | Methods and Compositions for Treating and Diagnosing Kidney Disease | LEAMON CHRISTOPHER PAUL (US) | 2012-10-25 | — | — | US | disclosed |
| US-20120270791-A1 | Methods and Compositions for Treating and Diagnosing Kidney Disease | LEAMON CHRISTOPHER PAUL (US) | 2012-10-25 | — | — | US | disclosed |
| US-20120065149-A1 | Vitamin receptor binding drug delivery conjugates | VLAHOV IONTCHO R (US) | 2012-03-15 | — | — | US | disclosed |
| US-8105568-B2 | Vitamin receptor binding drug delivery conjugates | ENDOCYTE, INC. (US) | 2012-01-31 | — | — | US | disclosed |
| US-20120022245-A1 | FOLATE TARGETING OF NUCLEOTIDES | PURDUE RESEARCH FOUNDATION (US) | 2012-01-26 | — | — | US | disclosed |
| US-20100104626-A1 | METHODS AND COMPOSITIONS FOR TREATING AND DIAGNOSING KIDNEY DISEASE | ENDOCYTE, INC. (US) | 2010-04-29 | — | — | US | disclosed |
| US-20100004276-A1 | VITAMIN RECEPTOR BINDING DRUG DELIVERY CONJUGATES | VLAHOV IONTCHO R | 2010-01-07 | — | — | US | disclosed |
| US-7601332-B2 | Minimized toxicity; eliminating pathogenic cell populations; synthesis; claimed intermediates | ENDOCYTE, INC. (US) | 2009-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022245-A1 | FOLATE TARGETING OF NUCLEOTIDES | FOLR1, FOLR2, DHFR | TSHR 1536/4885ALDH1A1 1932/4885NFKB1 860/4885 |
| US-20100004276-A1 | VITAMIN RECEPTOR BINDING DRUG DELIVERY CONJUGATES | VDR, CYP2R1, CYP24A1 | TSHR 377/4885ALDH1A1 931/4885NFKB1 2666/4885 |
| US-20100104626-A1 | METHODS AND COMPOSITIONS FOR TREATING AND DIAGNOSING KIDNEY DISEASE | VDR, GC, CYP24A1 | TSHR 428/4885ALDH1A1 2229/4885NFKB1 1821/4885 |
| US-20120065149-A1 | Vitamin receptor binding drug delivery conjugates | VDR, CYP2R1, CYP24A1 | TSHR 377/4885ALDH1A1 931/4885NFKB1 2666/4885 |
| US-20120270791-A1 | Methods and Compositions for Treating and Diagnosing Kidney Disease | VDR, GC, CYP24A1 | TSHR 428/4885ALDH1A1 2229/4885NFKB1 1821/4885 |
| US-20180215687-A1 | SYNTHESIS OF ARYL COMPOUNDS | UTS2R, UGT1A1, NAT1 | TSHR 530/4885ALDH1A1 145/4885NFKB1 1513/4885 |
| US-20160220694-A1 | Vitamin-Receptor Binding Drug Delivery Conjugates | VDR, CYP2R1, CYP24A1 | TSHR 371/4885ALDH1A1 672/4885NFKB1 2665/4885 |
| US-20140058063-A1 | VITAMIN RECEPTOR BINDING DRUG DELIVERY CONJUGATES | VDR, CYP2R1, CYP24A1 | TSHR 377/4885ALDH1A1 931/4885NFKB1 2666/4885 |
| US-20120329871-A1 | ANTIMICROBIAL COMPOUNDS | DPM1, NACA, CLPP | TSHR 4333/4885ALDH1A1 2802/4885NFKB1 1015/4885 |
| US-20170029359-A1 | ANTIMICROBIAL COMPOUNDS | MRPL21, SPOUT1, MPO | TSHR 4275/4885ALDH1A1 2054/4885NFKB1 784/4885 |
| US-20150189873-A1 | ANTIMICROBIAL COMPOUNDS | DPM1, NACA, CLPP | TSHR 4333/4885ALDH1A1 2802/4885NFKB1 1015/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.