Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | GABRA2 | P47869 | 7/20 | 0.52 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3500190 | 1.00 | KDM4E (0.55) | KDM4EPOLBGABRA2GABRB2GAA | |
| SCHEMBL3498736 | 0.91 | KDM4E (0.59) | KDM4EPOLBGABRA2GABRB2GAA | |
| SCHEMBL3498738 | 0.91 | KDM4E (0.59) | KDM4EPOLBGABRA2GABRB2GAA | |
| SCHEMBL3498388 | 0.89 | KDM4E (0.56) | KDM4EPOLBGABRA2GABRB2GAA | |
| SCHEMBL3498385 | 0.89 | KDM4E (0.56) | KDM4EPOLBGABRA2GABRB2GAA | |
| SCHEMBL3499344 | 0.87 | KDM4E (0.57) | KDM4EPOLBGABRA2GABRB2GAA | |
| SCHEMBL741904 | 0.86 | KDM4E (0.64) | KDM4EPOLBGABRA2GABRB2GAA | |
| SCHEMBL3499130 | 0.84 | GABRA2 (0.62) | KDM4EPOLBGABRA2GABRB2GAA | |
| SCHEMBL1638237 | 0.83 | KDM4E (0.61) | KDM4EPOLBGABRA2GABRB2GAA | |
| SCHEMBL3499179 | 0.83 | KDM4E (0.53) | KDM4EPOLBGABRA2GABRB2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-27 | — | — | US | disclosed |
| EP-1849465-A1 | AGENT FOR CONTROLLING FUNCTION OF GPR34 RECEPTOR | Takeda Pharmaceutical Company Limited (JP) | 2007-10-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | GPR34, GPR4, GPR6 | KDM4E 2059/4885POLB 4658/4885GABRA2 317/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.