SCHEMBL3500769

SCHEMBL3500769

OCCOc1cccc(O)c1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.54
MAPT P10636 2/20 0.54
GAA P10253 2/20 0.54
JAK2 O60674 1/20 0.54
IDO1 P14902 1/20 0.53
TP53 P04637 4/20 0.50
ALDH1A1 P00352 3/20 0.50
HPGD P15428 2/20 0.50
ALOX15 P16050 2/20 0.50
HSD17B10 Q99714 2/20 0.50
CYP3A4 P08684 2/20 0.50
MAPK1 P28482 2/20 0.50
KDM4E B2RXH2 1/20 0.50
ALOX12 P18054 1/20 0.50
RECQL P46063 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
ADAMTS4 O75173 1/20 0.46
EGFR P00533 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1030614 0.84 GAA (0.75) LMNAMAPTGAAJAK2IDO1
SCHEMBL8368458 0.83 LMNA (0.50) LMNAMAPTGAAJAK2IDO1
SCHEMBL28448694 0.82 LMNA (0.54) LMNAMAPTGAAJAK2TP53
SCHEMBL3922118 0.82 IDO1 (0.79) LMNAMAPTGAAJAK2IDO1
SCHEMBL7904569 0.82 ALDH1A1 (0.55) LMNAMAPTIDO1TP53ALDH1A1
SCHEMBL18152143 0.82 IDO1 (0.49) LMNAMAPTGAAJAK2IDO1
SCHEMBL7070645 0.81 IDO1 (0.55) LMNAMAPTGAAJAK2IDO1
SCHEMBL25409990 0.81 KDM4E (0.59) LMNAMAPTGAAJAK2TP53
SCHEMBL1052278 0.81 LMNA (0.54) LMNAMAPTGAAJAK2TP53
SCHEMBL4744929 0.80 TP53 (0.51) LMNAIDO1TP53ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107530405-A Insulin analogs containing glucose-regulated conformational converters 卡斯西部储备大学 2018-01-02 CN claimed
US-5750093-A 33 Lipomelanin sunscreen composition DUSA PHARMACEUTICALS, INC. (CA) 1998-05-12 US claimed
US-5643554-A Lipomelanim composition DUSA PHARMACEUTICALS, INC. (CA) 1997-07-01 US claimed
US-20230391944-A1 COMPOUND, METHOD FOR PRODUCING COMPOUND, ADHESIVE COMPOSITION AND ADHESIVE TAPE SEKISUI CHEMICAL CO., LTD. (JP) 2023-12-07 US disclosed
US-20230340307-A1 COMPOUND, METHOD FOR PRODUCING COMPOUND, ADHESIVE COMPOSITION AND ADHESIVE TAPE SEKISUI CHEMICAL CO., LTD. (JP) 2023-10-26 US disclosed
EP-4206255-A1 COMPOUND, METHOD FOR PRODUCING COMPOUND, ADHESIVE COMPOSITION AND ADHESIVE TAPE SEKISUI CHEMICAL CO., LTD. (JP) 2023-07-05 EP disclosed
EP-4206174-A1 COMPOUND, METHOD FOR PRODUCING COMPOUND, ADHESIVE COMPOSITION AND ADHESIVE TAPE SEKISUI CHEMICAL CO., LTD. (JP) 2023-07-05 EP disclosed
EP-4135529-A1 PROCESSES AND METHODS FOR PRODUCING AN EDIBLE CREAM FROM OLIVES Masanés Autard, Tomas (US) 2023-02-22 EP disclosed
CN-110505873-B Intranasal epinephrine formulations and methods of treating disease 爱奇司治疗公司 2022-12-30 CN disclosed
CN-115443260-A Compound, method for producing compound, adhesive composition, and adhesive tape 积水化学工业株式会社 2022-12-06 CN disclosed
CN-108431216-B Codon-optimized reduced size ATP7A CDNA and use for treating copper transport disorders 美国政府(由卫生和人类服务部的部长所代表) 2022-08-05 CN disclosed
EP-1903028-A1 Conjugates of glutamate and NMDA receptor channel blockers without excito-toxic effects Tschollar,, Werner (CH) 2008-03-26 EP disclosed
CN-101137326-A Novel differential imaging method MEDI PHYSICS INC (US) 2008-03-05 CN disclosed
US-7094532-B2 Genetic mutation underlying orthostatic intolerance and diagnostic and therapeutic methods relating thereto VANDERBILT UNIVERSITY (US) 2006-08-22 US disclosed
WO-2001048246-A1 GENETIC MUTATION UNDERLYING ORTHOSTATIC INTOLERANCE AND DIAGNOSTIC AND THERAPEUTIC METHODS RELATING THERETO VANDERBILT UNIVERSITY (US) 2001-07-05 WO disclosed
US-5750093-A 33 Lipomelanin sunscreen composition DUSA PHARMACEUTICALS, INC. (CA) 1998-05-12 US disclosed
US-5643554-A Lipomelanim composition DUSA PHARMACEUTICALS, INC. (CA) 1997-07-01 US disclosed
EP-0696305-A1 SUNSCREEN PRODUCT AND PROCESS FOR THE PRODUCTION THEREOF DUSA PHARMACEUTICALS, INC. (CA) 1996-02-14 EP disclosed
WO-1994025532-A1 SUNSCREEN PRODUCT AND PROCESS FOR THE PRODUCTION THEREOF DUSA PHARMACEUTICALS, INC. (CA) 1994-11-10 WO disclosed
US-4022664-A HYDROLYSIS EISAI CO., LTD. (JA) 1977-05-10 US disclosed