Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | JAK2 | O60674 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8897368 | 0.87 | LMNA (0.52) | LMNAMAPTGAAJAK2IDO1 | |
| SCHEMBL11808177 | 0.85 | IDO1 (0.41) | LMNAMAPTGAAJAK2IDO1 | |
| SCHEMBL3500769 | 0.83 | LMNA (0.54) | LMNAMAPTGAAJAK2IDO1 | |
| SCHEMBL1837129 | 0.82 | LMNA (0.49) | LMNAMAPTGAAJAK2HTR1A | |
| SCHEMBL14060482 | 0.82 | IDO1 (0.56) | LMNAMAPTGAAJAK2IDO1 | |
| SCHEMBL1030614 | 0.81 | GAA (0.75) | LMNAMAPTGAAJAK2IDO1 | |
| SCHEMBL1838521 | 0.81 | CYP1A2 (0.50) | LMNAMAPTGAAJAK2HTR1A | |
| Ammonia Solution, Strong SCHEMBL27537195 | 0.81 | LMNA (0.47) | LMNAMAPTGAAJAK2HTR1A | |
| SCHEMBL1840614 | 0.79 | LMNA (0.47) | LMNAMAPTGAAJAK2HTR1A | |
| SCHEMBL561025 | 0.79 | LMNA (0.43) | LMNAMAPTGAAJAK2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999047578-A1 | SURFACE ACTIVE POLYESTERS | REICHHOLD, INC. (US) | 1999-09-23 | — | — | WO | disclosed |