SCHEMBL6670670

SCHEMBL6670670

CCOC(=O)C(O)C(CC(=O)O)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.38
EGLN1 Q9GZT9 1/20 0.37
MEN1 O00255 1/20 0.36
NPC1 O15118 1/20 0.36
KMT2A Q03164 1/20 0.36
ALDH1A1 P00352 3/20 0.36
SLC22A6 Q4U2R8 1/20 0.36
LMNA P02545 1/20 0.34
HSD17B10 Q99714 1/20 0.34
GPR84 Q9NQS5 2/20 0.33
CYP2D6 P10635 1/20 0.33
ALOX15 P16050 1/20 0.33
PIN1 Q13526 1/20 0.33
MGAM O43451 1/20 0.33
GAA P10253 1/20 0.33
SI P14410 1/20 0.33
MGAM2 Q2M2H8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6668703 0.90 TDP1 (0.41) TDP1SMN1; SMN2EGLN1MEN1NPC1
SCHEMBL6668710 0.86 MGAM (0.41) TDP1MEN1NPC1KMT2AALDH1A1
SCHEMBL6670982 0.85 TDP1 (0.46) TDP1SMN1; SMN2ALDH1A1SLC22A6LMNA
SCHEMBL3500864 0.82 TDP1 (0.52) TDP1SMN1; SMN2KMT2ASLC22A6LMNA
SCHEMBL19323989 0.81 TDP1 (0.48) TDP1SMN1; SMN2EGLN1MEN1NPC1
SCHEMBL9794612 0.81 TDP1 (0.48) TDP1SMN1; SMN2EGLN1MEN1NPC1
SCHEMBL29924533 0.80 GPR84 (0.43) TDP1GPR84
SCHEMBL9782172 0.79 ALDH1A1 (0.39) SMN1; SMN2EGLN1MEN1NPC1KMT2A
SCHEMBL28856632 0.79 GPR84 (0.46) GPR84
SCHEMBL9462134 0.78 TDP1 (0.48) TDP1SMN1; SMN2EGLN1MEN1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0130482-B1 DIAMINOCYCLOHEXANE PLATINUM COMPLEXES, PROCESS FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME Research Corporation (US) 1988-12-28 EP claimed
US-20140150135-A1 Synthetic Pathway for Biological Carbon Dioxide Sequestration NORTH CAROLINA STATE UNIVERSITY (US) 2014-05-29 US disclosed
EP-0831767-B1 ALPHA HYDROXYACID ESTERS FOR SKIN AGING YU RUEY J (US) 2004-09-22 EP disclosed
EP-0831767-A4 ALPHA HYDROXYACID ESTERS FOR SKIN AGING YU RUEY J (US) 2000-05-17 EP disclosed
EP-0831767-A1 ALPHA HYDROXYACID ESTERS FOR SKIN AGING Yu, Ruey J., Dr. (US) 1998-04-01 EP disclosed
US-5686489-A TOPICALLY APPLIED TO INDUCE GLYCOSAMINOGLYCAN, PROTEOGLYCAN, COLLAGEN AND ELASTIN BIOSYNTHESIS; WRINKLE RESISTANCE TRISTRATA TECHNOLOGY, INC. (US) 1997-11-11 US disclosed
WO-1996040047-A1 ALPHA HYDROXYACID ESTERS FOR SKIN AGING YU RUEY J (US) 1996-12-19 WO disclosed
EP-0130482-B1 DIAMINOCYCLOHEXANE PLATINUM COMPLEXES, PROCESS FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME Research Corporation (US) 1988-12-28 EP disclosed
US-4758588-A Diaminocyclohexane platinum complexes RESEARCH CORPORATION TECHNOLOGIES (US) 1988-07-19 US disclosed
US-4661516-A WATER SOLUBLE, ANTITUMOR AGENTS RESEARCH CORPORATION (US) 1987-04-28 US disclosed
EP-0130482-A1 Diaminocyclohexane platinum complexes, process for preparing same and pharmaceutical compositions containing same Research Corporation (US) 1985-01-09 EP disclosed