Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 11/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.52 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.52 |
| ▸ | RELA | Q04206 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3498170 | 0.88 | MRGPRX4 (0.55) | MRGPRX4RAB9ASMN1; SMN2TP53PKM | |
| SCHEMBL29346854 | 0.86 | SLC7A5 (0.58) | MRGPRX4RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL31068535 | 0.86 | SLC7A5 (0.58) | MRGPRX4RAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL5271801 | 0.84 | MRGPRX4 (0.73) | MRGPRX4RAB9ASMN1; SMN2TP53PKM | |
| SCHEMBL14539034 | 0.84 | RAB9A (0.62) | MRGPRX4RAB9ASMN1; SMN2TP53PKM | |
| SCHEMBL3500015 | 0.82 | MRGPRX4 (0.49) | MRGPRX4RAB9ASMN1; SMN2TP53NFKB1 | |
| SCHEMBL864218 | 0.81 | MRGPRX4 (0.54) | MRGPRX4RAB9ASMN1; SMN2TP53PKM | |
| SCHEMBL21221834 | 0.78 | MRGPRX4 (0.64) | MRGPRX4RAB9ASMN1; SMN2TP53PKM | |
| SCHEMBL2440071 | 0.78 | SMN1; SMN2 (0.55) | RAB9ASMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL8586218 | 0.78 | MRGPRX4 (0.60) | MRGPRX4RAB9ASMN1; SMN2TP53PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-05-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130737-A1 | Regulating Agent of GPR34 Receptor Function | GPR34, GPR4, GPR6 | MRGPRX4 48/4885RAB9A 2269/4885SMN1; SMN2 4779/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.