SCHEMBL3500948

SCHEMBL3500948

CCN(CC)/N=N\c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 7/20 0.55
▸ ALDH1A1 P00352 3/20 0.48
▸ TSHR P16473 2/20 0.43
▸ TDP1 Q9NUW8 2/20 0.43
▸ MAPK1 P28482 2/20 0.43
▸ HSD17B10 Q99714 1/20 0.43
▸ RAB9A P51151 6/20 0.38
▸ NPC1 O15118 5/20 0.38
▸ MEN1 O00255 4/20 0.38
▸ KMT2A Q03164 4/20 0.38
▸ PKM P14618 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ NPSR1 Q6W5P4 1/20 0.37
▸ CASP3 P42574 2/20 0.36
▸ SENP8 Q96LD8 2/20 0.36
▸ SENP7 Q9BQF6 2/20 0.36
▸ SENP6 Q9GZR1 2/20 0.36
▸ CYP1A1 P04798 1/20 0.35
▸ CYP1B1 Q16678 1/20 0.35
▸ SMN1; SMN2 Q16637 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL973245 1.00 MAPT (0.55) MAPTALDH1A1TSHRTDP1MAPK1
SCHEMBL973244 1.00 MAPT (0.55) MAPTALDH1A1TSHRTDP1MAPK1
Water SCHEMBL5373028 0.98 MAPT (0.53) MAPTALDH1A1TSHRTDP1MAPK1
SCHEMBL9107945 0.83 ALDH1A1 (0.44) MAPTALDH1A1TSHRTDP1MAPK1
SCHEMBL22390704 0.83 ALDH1A1 (0.44) MAPTALDH1A1TSHRTDP1MAPK1
SCHEMBL22390702 0.83 ALDH1A1 (0.44) MAPTALDH1A1TSHRTDP1MAPK1
SCHEMBL4416832 0.80 ALDH1A1 (0.47) MAPTALDH1A1TSHRTDP1MAPK1
SCHEMBL14366560 0.80 MAPT (0.58) MAPTALDH1A1TDP1MAPK1RAB9A
SCHEMBL2107416 0.78 MAPT (0.56) MAPTALDH1A1TDP1RAB9ANPC1
SCHEMBL6517951 0.78 MAPT (0.56) MAPTALDH1A1TSHRTDP1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160369237-A1 METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY ADVANCED CELL TECH INC (US) 2016-12-22 — — US disclosed
US-20100184033-A1 METHODS TO ACCELERATE THE ISOLATION OF NOVEL CELL STRAINS FROM PLURIPOTENT STEM CELLS AND CELLS OBTAINED THEREBY Lineage Cell Therapeutics, Inc. 2010-07-22 — — US disclosed
US-20080226601-A1 Herpes Virus-Based Compositions and Methods of Use in the Prenatal and Perinatal Periods UNIVERSITY OF ROCHESTER (US) 2008-09-18 — — US disclosed
EP-1903873-A2 HERPES VIRUS-BASED COMPOSITIONS AND METHODS OF USE IN THE PRENATAL AND PERINATAL PERIODS THE UNIVERSITY OF ROCHESTER (US) 2008-04-02 — — EP disclosed
US-20080070303-A1 Using myocardial and/or muscle progenitor cells as modeling tool in tissue engineering; regenerative medicine and organ replacement ADVANCED CELL TECHNOLOGY 2008-03-20 — — US disclosed
WO-2006135602-A2 HERPES VIRUS-BASED COMPOSITIONS AND METHODS OF USE IN THE PRENATAL AND PERINATAL PERIODS UNIVERSITY OF ROCHESTER (US) 2006-12-21 — — WO disclosed
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