SCHEMBL22390704

SCHEMBL22390704

CCCN(CCC)N=Nc1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.44
▸ TSHR P16473 2/20 0.41
▸ MAPK1 P28482 2/20 0.41
▸ TDP1 Q9NUW8 2/20 0.41
▸ HSD17B10 Q99714 1/20 0.41
▸ MAPT P10636 6/20 0.40
▸ POLB P06746 1/20 0.38
▸ GAA P10253 1/20 0.38
▸ MEN1 O00255 3/20 0.35
▸ KMT2A Q03164 3/20 0.35
▸ RAB9A P51151 2/20 0.35
▸ NPC1 O15118 2/20 0.35
▸ PKM P14618 1/20 0.35
▸ HTT P42858 1/20 0.35
▸ TP53 P04637 1/20 0.34
▸ SIGMAR1 Q99720 1/20 0.34
▸ FTO Q9C0B1 1/20 0.34
▸ DRD3 P35462 1/20 0.33
▸ CYP1A1 P04798 1/20 0.33
▸ CYP1B1 Q16678 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9107945 1.00 ALDH1A1 (0.44) ALDH1A1TSHRMAPK1TDP1HSD17B10
SCHEMBL22390702 1.00 ALDH1A1 (0.44) ALDH1A1TSHRMAPK1TDP1HSD17B10
SCHEMBL973245 0.83 MAPT (0.55) ALDH1A1TSHRMAPK1TDP1HSD17B10
SCHEMBL3500948 0.83 MAPT (0.55) ALDH1A1TSHRMAPK1TDP1HSD17B10
SCHEMBL973244 0.83 MAPT (0.55) ALDH1A1TSHRMAPK1TDP1HSD17B10
Water SCHEMBL5373028 0.81 MAPT (0.53) ALDH1A1TSHRMAPK1TDP1HSD17B10
SCHEMBL10779390 0.80 ALDH1A1 (0.37) ALDH1A1TSHRMAPK1TDP1HSD17B10
SCHEMBL13803508 0.79 ALDH1A1 (0.57) ALDH1A1TSHRMAPK1TDP1HSD17B10
SCHEMBL10598054 0.79 ALDH1A1 (0.57) ALDH1A1TSHRMAPK1TDP1HSD17B10
SCHEMBL7741815 0.78 TP53 (0.36) ALDH1A1TSHRMAPK1TDP1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240254284-A1 UNSATURATED CYCLIC ANHYDRIDE END CAPPED POLYIMIDES AND POLYAMIC ACIDS AND PHOTOSENSITIVE COMPOSITIONS THEREOF PROMERUS, LLC (US) 2024-08-01 — — US claimed
US-20200283580-A1 UNSATURATED CYCLIC ANHYDRIDE END CAPPED POLYIMIDES AND POLYAMIC ACIDS AND PHOTOSENSITIVE COMPOSITIONS THEREOF PROMERUS, LLC (US) 2020-09-10 — — US claimed
US-12180385-B2 Shelf life stable and improved mass polymerizable polycyclic-olefinic compositions PROMERYS, LLC (US) 2024-12-31 — — US disclosed
US-20240254284-A1 UNSATURATED CYCLIC ANHYDRIDE END CAPPED POLYIMIDES AND POLYAMIC ACIDS AND PHOTOSENSITIVE COMPOSITIONS THEREOF PROMERUS, LLC (US) 2024-08-01 — — US disclosed
US-11845880-B2 Polycyclic-olefinic compositions for low-loss films having improved thermal properties PROMERUS, LLC (US) 2023-12-19 — — US disclosed
EP-4237461-A1 SHELF LIFE STABLE AND IMPROVED MASS POLYMERIZABLE POLYCYCLIC-OLEFINIC COMPOSITIONS Promerus, LLC (US) 2023-09-06 — — EP disclosed
EP-4237460-A1 POLYCYCLIC-OLEFINIC COMPOSITIONS FOR LOW-LOSS FILMS HAVING IMPROVED THERMAL PROPERTIES Promerus, LLC (US) 2023-09-06 — — EP disclosed
CN-116457380-A Improved polycycloolefin compositions having stable shelf life and capable of bulk polymerization 普罗米鲁斯有限责任公司 2023-07-18 — — CN disclosed
CN-116368165-A Polycyclic olefin composition for low loss films with improved thermal properties 普罗米鲁斯有限责任公司 2023-06-30 — — CN disclosed
US-20220135832-A1 SHELF LIFE STABLE AND IMPROVED MASS POLYMERIZABLE POLYCYCLIC-OLEFINIC COMPOSITIONS PROMERUS, LLC (US) 2022-05-05 — — US disclosed
US-20220135831-A1 POLYCYCLIC-OLEFINIC COMPOSITIONS FOR LOW-LOSS FILMS HAVING IMPROVED THERMAL PROPERTIES PROMERUS, LLC (US) 2022-05-05 — — US disclosed
WO-2022094236-A1 SHELF LIFE STABLE AND IMPROVED MASS POLYMERIZABLE POLYCYCLIC-OLEFINIC COMPOSITIONS PROMERUS, LLC (US) 2022-05-05 — — WO disclosed
WO-2022094232-A1 POLYCYCLIC-OLEFINIC COMPOSITIONS FOR LOW-LOSS FILMS HAVING IMPROVED THERMAL PROPERTIES PROMERUS, LLC (US) 2022-05-05 — — WO disclosed
US-20200283580-A1 UNSATURATED CYCLIC ANHYDRIDE END CAPPED POLYIMIDES AND POLYAMIC ACIDS AND PHOTOSENSITIVE COMPOSITIONS THEREOF PROMERUS, LLC (US) 2020-09-10 — — US disclosed
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